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1

A pilot study to establish an ovalbumin-induced atopic dermatitis minipig model

100%
Kim Y. K., Lee J. Y., Hwang H., Suh H. N.
Journal of Veterinary Research
|
2021
|
tom 65
|
nr 3
2

Immune balance in critically ill patients

84%
Pinsky M. R.
Archivum Immunologiae et Therapiae Experimentalis
|
2000
|
tom 48
|
nr 6 Spec.Iss.
439-442
3

Adaptive immune cell dysregulation and role in acute pancreatitis disease progression and treatment

84%
Fonteh P., Smith M., Brand M.
Archivum Immunologiae et Therapiae Experimentalis
|
2018
|
tom 66
|
nr 3
4
Content available remote

Functional analysis of eicosanoids from white blood cells in sepsis and SIRS

84%
Baenkler M., Leykauf M., John S.
Journal of Physiology and Pharmacology. Supplement
|
2006
|
tom 57
|
nr 12
25-33
Sepsis and SIRS are affections with major alterations in inflammatory activity. The impact of prostaglandins (PG) and leukotrienes (LT) produced from white blood cells (WBC) in this context is not completely understood. Thirty nine patients with sepsis or SIRS were investigated in comparison to 10 healthy controls. WBC were collected and separately exposed to arachidonic acid (AA) or to nothing else. After centrifugation, the generated PGE2 and LTCDE4 with or without stimulation were measured in the supernatant. LT-levels were significantly higher during sepsis/SIRS than in controls whereas PG-levels of patients were decreased to those of controls in basic condition. The relation between the level with and without stimulation showed a significant higher ratio in PG in contrast to LTs. The survivor’s ratio in LT levels was significantly higher than that of non-survivors, which did not differ from controls. Generation of LT from WBC is enhanced during sepsis/SIRS, but LT generation after stimulation only in survivors but not in non-survivors. This inability of WBC to generate LT during sepsis in non-survivors could be predictive regarding the outcome of sepsis/SIRS and may be part of the “immunoparalysis” seen during sepsis in association with bad outcome.
5

Evaluation of serum and urine neutrophil gelatinase-associated lipocalin and cystatin C as biomarkers of acute kidney injury in horses

84%
Siwinska N., Zak A., Paslawska U.
Journal of Veterinary Research
|
2021
|
tom 65
|
nr 2
6

What is the cause and possible mechanism of multiorgan failure in acute pancreatitis?

84%
Rydzewska G.
Journal of Physiology and Pharmacology. Supplement
|
1998
|
tom 49
|
nr 2
7

Effect of cardiopulmonary bypass on neutrophil activity in pediatric open-heart surgery

84%
Pasnik J., Siniewicz K., Moll J. A., Moll J., Baj Z., Sysa A., Zeman K.
Archivum Immunologiae et Therapiae Experimentalis
|
2005
|
tom 53
|
nr 3
8

Molecular mechanisms and pathological consequences of endotoxin tolerance and priming

67%
Morris M., Li L.
Archivum Immunologiae et Therapiae Experimentalis
|
2012
|
tom 60
|
nr 1
9

Evaluation of tissue trauma and healing on the basis of tumour necrosis factor-alpha, interleukin-6, and C-reactive protein in peripheral blood during and after pyometra in bitches

67%
Toydemir Karabulut T. S. F., Sonmez K.
Medycyna Weterynaryjna
|
2018
|
tom 74
|
nr 10
In this study, inflammation in the blood of bitches with pyometra (PG) was compared before and 15 days after ovariohysterectomy (OVH). The results were compared with those for control dioestrus bitches (CG) to reveal the evidence of inflammation in blood after a routine surgery. Inflammation was tracked by tumour necrosis factor-alpha (TNF-α), interleukine-6 (IL-6) and C-reactive protein (CRP), using immunocytochemistry (ICC) and immunofluorescence capture of blood cells in cell blocks. ICC is performed mainly during routine cytological examinations, whereas the use of cell blocks in blood examination is uncommon. Insofar as we know, this is the first study using cell block techniques on canine blood samples. Three commercially available antibodies against TNF-α, IL-6 and CRP, forming two panels, were evaluated. A standard streptoavidin-biotin complex technique was used for ICC. TNF-α and IL-6 labelling was scored for colour and intensity, and CRP for immunofluorescence capture. TNF-α and IL-6 colour and intensity scores differed significantly between the PG and CG groups, and were higher in PG before OVH (P < 0.01, P < 0.01, P < 0.001, P < 0.01, respectively). IL-6 intensity was significantly greater in PG 15 days after OVH (P < 0.05). CRP capture in PG was strong before OVH and high in both groups 15 days later. Low-dose anti-inflammatory agents or an anti-cytokine therapy may be useful in pyometra treatment in the future because these treatments may offer protection from systemic inflammatory response syndrome before and after OVH.
10

Lactoferrin effects on the in vitro immune response in critically III patients

67%
Adamik B., Zimecki M., Wlaszczyk A., Berezowicz P., Kubler A.
Archivum Immunologiae et Therapiae Experimentalis
|
1998
|
tom 46
|
nr 3
11

Monocyte-related immunopathologies in trauma patients

67%
Laudanski K., Wyczechowska D.
Archivum Immunologiae et Therapiae Experimentalis
|
2005
|
tom 53
|
nr 4
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