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1

Rescue of sympathetic neurons from NGF-withdrawal apoptosis by adenosine

100%

Wakade A. R., Wakade T. D., Przywara D. A.

Cellular and Molecular Biology Letters

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1999

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tom 04

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nr 3

2

Identification of a presynaptic cannabinoid CB1 receptor in the guinea-pig atrium and sequencing of the guinea-pig CB1 receptor

72%

Kurz C. M., Gottschalk C., Schlicker E., Kathmann M.

Journal of Physiology and Pharmacology

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2008

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tom 59

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nr 1

We studied whether cannabinoid CB1 receptors occur on the sympathetic neurones innervating the guinea-pig atrium and renal cortex. Atrial and cortical kidney pieces preincubated with [3H]-noradrenaline were superfused and the electrically (3 Hz)-evoked tritium overflow was examined. The evoked overflow in atrium was inhibited by the cannabinoid agonist WIN 55,212-2 maximally by 35%; its concentration-response curve was shifted to the right by the CB1 antagonist rimonabant (pA2 8.3), which, by itself, did not affect the evoked overflow. The evoked overflow in the renal cortex was not altered by WIN 55,212-2. The muscarinic agonist oxotremorine and prostaglandin E2 inhibited the evoked overflow maximally by 55 and 65% in atrium and by 80 and 55% in kidney, respectively. Furthermore, the nucleotide sequence of the guinea-pig CB1 receptor was determined (GenBank DQ355990). The deduced amino acid sequence has a high homology to the corresponding sequence of man (98.7%) and rat or mouse (99.2%). In conclusion, presynaptic CB1 receptors leading to inhibition of noradrenaline release occur in guinea-pig atrium but not renal cortex. The deduced amino acid sequence of the guinea-pig CB1 receptor shows a homology of 99% to the CB1 receptor sequence of rodents and humans.

3

Modulation of the composition of AP-1 complex and its impact on transcriptional activity

58%

Kaminska B., Pyrzynska B., Ciechomska I., Wisniewska M.

Acta Neurobiologiae Experimentalis

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2000

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tom 60

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nr 3

4

Synaptogenesis and structure of the autonomic ganglia

58%

Majewski M.

Folia Morphologica. Supplement

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1999

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tom 58

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nr 2

5

Specific distribution pattern of nerve fibers containing catecholamine-synthesizing enzymes, neuropeptide Y [NPY] and C-terminal flanking peptide of NPY [CPON] in the pineal gland of the chinchilla [Chinchilla laniger] - an immunohistochemical study

58%

Nowicki M., Wojtkiewicz J., Seremak B., Sulik M., Ostaszewski J., Lewczuk B., Majewski M., Przybylska-Gornowicz B.

Folia Histochemica et Cytobiologica

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2003

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tom 41

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nr 4

6

Immunohistochemical characterisation of cholinergic neurons in the anterior pelvic ganglion of the male pig

58%

Kaleczyc J., Wasowicz K., Klimczuk M., Czaja K., Lakomy M.