The aim of this study was a comparison of results of the bile acids test and antipyrine test on calves. The experiment was carried out on 10 healthy calves of Black and White breed. In each subject the antipyrine test was performed on day 10 and 20 after birth. The concentration of bile acids in plasma before feeding (fasting - f SKŻ) and 2 hours after feeding (p SKŻ) were also determined. A correlation analysis was used to compare results of the bile acids test with the antipyrine test. The obtained results indicated that the hepatic biotransformation rate of antipyrine in calves increased significantly with age. The concentrations of fasting bile acids in the plasma of 10 day-old calves and 20 day-old calves were not significantly different. Similar results were obtained in the case of postfeeding bile acids concentrations. In contrast, the concentration of bile acids in plasma 2 hours after feeding was significantly (P<0.01) higher (both in 10 day-old and 20 day-old calves) than the concentration of fasting bile acids. It was determined that fasting and postfeeding concentrations of bile acids in plasma and values of metabolic clearance of antipyrine (C1A) were significantly (P<0.01) correlated.
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