The review presents a brief description of the most important traits of 10 prion diseases in humans and in animals. The diseases are defined in terms of their aetiology, latent period, signs/symptoms and potential transmission to other animals or humans in the case of affected animals. The time-period in which the disease may be diagnosed, natural reservoirs of infection and, in the case of prion diseases in humans, two newly described varieties of the diseases are presented.
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