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Evaluation of bone formation in fetal skeletons following prenatal paracetamol administration in single alizarin-stained specimens in Wistar rats

100%

Burdan F.

Folia Morphologica

2000

tom 59

nr 3

The study was undertaken to evaluate the effect of paracetamol on skeleton in Wistar rats. The drug was administered orally, once a day, in three doses: P1 — 3.5 mg/kg, P2 — 35.0 mg/kg, P3 — 350.0 mg/kg. The foetuses were delivered by laparotomy on the 21st day of pregnancy and fixed in alcohol. The skeletons were stained with alizarin. Insignificant differences of bone malformations were found.

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1 Folia Morphologica

1 Burdan F.

1 2000

Wyniki wyszukiwania

Evaluation of bone formation in fetal skeletons following prenatal paracetamol administration in single alizarin-stained specimens in Wistar rats