Wyniki wyszukiwania

1

Microstructure of soy protein products

100%

Cserhalmi Z., Katsaras K., Czukor B.

Polish Journal of Food and Nutrition Sciences

|

1998

|

tom 07

|

nr 2 Suppl.

2

Immunoexpression of nm23 in advanced esophageal squamous cell carcinoma

75%

Szumilo J., Skomra D., Chibowski D., Dabrowski A., Wallner G., Maciejewski R.

Folia Histochemica et Cytobiologica

|

2002

|

tom 40

|

nr 4

3

Expression profile of gene p53 and H2b-H4 histone encoding genes i vulvar neoplasts at various stages of advancement of the neoplastic process

75%

Paul M., Mazurek U., Kusmierz D., Witek A., Wilczok T.

Folia Histochemica et Cytobiologica. Supplement

|

2001

|

tom 39

|

nr 1

4

Gene trapping: An antibody-dependent approach for verifying integration in your favorite gene

63%

Gorelik A., Sapir T., Reiner O.

Cellular and Molecular Biology Letters

|

2008

|

tom 13

|

nr 4

614-620

Gene trapping is used to introduce genome-wide insertional mutations in embryonic stem cells. Determining the integration site is based on highthroughput PCR, which has inevitable possibilities for mistakes, thus necessitating clone verification prior to the generation of mutant mice. Here, we propose a rapid method to validate gene identity based on the fact that many high throughput gene-trapping integrations result in fusion proteins encompassing the N-terminal portion of the gene of interest and LacZ being expressed in embryonic stem cells. Our method utilizes an immunoprecipitation assay using a specific N-terminal-directed antibody to the protein product of the gene of interest followed by a color LacZ assay of the immunoprecipitate, strongly supporting the formation of a fusion protein when the color develops.

5

Expression of C-ERBB2 and P65 genes and their protein products in follicular neoplasms of thyroid gland

63%

Czyz W., Balcerczak E., Rudowicz M., Niewiadomska H., Pasieka Z., Kuzdak K., Mirowski M.

Folia Histochemica et Cytobiologica

|

2003

|

tom 41

|

nr 2

6

Cloning of the lymphoid enhancer binding factor-1 [Lef-1] cDNA from rat kidney: Homology to the mouse sequence

63%

Kobielak K., Kobielak A., Trzeciak W. H.

Acta Biochimica Polonica

|

1999

|

tom 46

|

nr 4

We have cloned and sequenced rat cDNA that encodes the Lef-1 protein. The cDNA, containing 1194 nt exhibits 94% similarity to the mouse Lef-1 cDNA. The deduced amino-acids sequence of rat Lef-1 protein, consisting of 397 amino acids, exhibited 98% homology with the known sequence of mouse Lef-1 protein.

7

N-myc downstream regulated 1 gene and its place in the cellular machinery

51%

Kitowska A., Pawelczyk T.

Acta Biochimica Polonica

|

2010

|

tom 57

|

nr 1

15-21

The exact function of the protein product of N-myc downstream regulated 1 gene (NDRG1) is unclear. Depending on the tissue type the NDRG1 protein is localized in the cytoplasm, nucleus, mitochondrion or membranes. Moreover, the expression of NDRG1 may be altered by several factors such as hypoxia, heavy metals, DNA damage, hormones, oncogene, and tumor-suppressor genes. A number of studies emphasize the role of NDRG1 in cancerogenesis. Presumably NDRG1 participates in angiogenesis, metastases, and mechanisms leading to anti-cancer drug resistance. This review summarizes current knowledge about the NDRG1 gene and the position of NDRG1 protein in the cellular machinery. The role of NDRG1 in cancer pathogenesis and its possible usefulness as a prognostic factor for patients with cancer is also discussed.

Ograniczanie wyników

Microstructure of soy protein products

Immunoexpression of nm23 in advanced esophageal squamous cell carcinoma

Expression profile of gene p53 and H2b-H4 histone encoding genes i vulvar neoplasts at various stages of advancement of the neoplastic process

Gene trapping: An antibody-dependent approach for verifying integration in your favorite gene

Expression of C-ERBB2 and P65 genes and their protein products in follicular neoplasms of thyroid gland

Cloning of the lymphoid enhancer binding factor-1 [Lef-1] cDNA from rat kidney: Homology to the mouse sequence

N-myc downstream regulated 1 gene and its place in the cellular machinery