Wyniki wyszukiwania

1

Assessment of the value of doubled haploids as progenitors in cocoa [Theobroma cacao L.] breeding

100%

Sounigo O., Lachenaud P., Bastide P., Cilas C., N'Goran J., Lanaud C.

Journal of Applied Genetics

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2003

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tom 44

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nr 3

2

Sequence heterogeneity of the envelope-like domain in cultivated allotetraploid Gossypium species and their diploid progenitors

84%

Hafez E. E., Abdel G. A. A., Paterson A. H., Zaki E. A.

Journal of Applied Genetics

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2009

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tom 50

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nr 1

17-23

Retroviral envelope (env)-like sequences in 2 cultivated allotetraploid cottons and their diploid progenitors have been identified and characterized in this study. DNA sequence analysis reveals that these sequences are heterogeneous. The observed sequence diversity, however, seems to preserve coding information. This is evidenced by the detection of the transmembrane domain (TM), which is the most conserved feature of the divergent retroviral env genes. The high ratio of synonymous to nonsynonymous changes suggests that these sequences are evolving under purifying selection. Phylogenetic analysis shows that Gossypium sequences closely cluster with a lineage of plant endogenous retroviruses that have an env-like gene. These results provide evidence for the antiquity and the wide diversity of env-like sequences in the Gossypium genome.

3

Beta-carotene and arachidonic acid induced DNA methylation and the regulation of pro-chemotactic activity of endothelial cells and its progenitors

84%

Kiec-Wilk B., Polus A., Mikolajczyk M., Mathers J. C.

Journal of Physiology and Pharmacology

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2007

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tom 58

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nr 4

DNA methylation is one of the important mechanisms regulating gene expression. Since beta-carotene (BC) was shown to have pro-chemotactic activity and stimulates expression of pro-angiogenic genes, this study was undertaken to define the possible changes in DNA methylation in endothelial cell and its progenitors in the presence of BC. The culture medium for human umbilical vein endothelial cells (HUVEC) and endothelial progenitor cells (EPC) was supplemented with BC (1 - 10 µM) with the presence of arachidonic acid (AA) (3 µM). Global DNA methylation tended to be lower in both endothelial cell lines, after incubation with BC and AA. HUVEC incubated with AA demonstrated the lowest DNA methylation. The decrease of DNA methylation in EPC, induced by BC, was concentration - dependent. The microarray study revealed, that the angiogenesis and homing – related genes were mostly influenced by BC and AA in investigated cells. Our results indicate that BC and AA-induced DNA hypomethylation in EPC and HUVEC, might be a mechanism which may alter gene expression in endothelial cells what in certain conditions may be connected with the suggested pro-malignant effect of this compounds.

4

The marrow cell continuum: stochastic determinism

84%

Quesenberry P., Abedi M., Dooner M., Colvin G., Sanchez-Guijo F. M., Aliotta J., Pimentel J., Dooner G., Greer D., Demers D., Keaney P., Peterson A., Luo L., Foster B.

Folia Histochemica et Cytobiologica

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2005

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tom 43

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nr 4

5

The comparison of multipotential for differentiation of progenitor mesenchymal-like stem cells obtained from livers of young and old rats

67%

Tarnowski M., Koryciak-Komarska H., Czekaj P., Sebesta R., Czekaj T. M., Urbanek K., Likus W., Malinowska-Kolodziej I., Plewka D., Nowaczyk-Dura G., Wiaderkiewicz R., Sieron A. L.