The objective of the studies was to evaluate the effects of Isoprivet on the percentage of TCD4 and TCD8 lymphocytes in cats with the feline respiratory disease complex (FRDC) and the therapy of FRDC. It was found that Isoprivet used three times at 2 or 7 day intervals in cats with FRDC appeared to be a potent stimulator of cellular immune response. This activity was evaluated by a flow cytometry on the basis of the percentage of CD4 and CD8 molecules on T lymphocytes and their relative proportions. Good therapeutic effect and a shortening of convalescence were obtained in cats with FRDC after three subcutaneous Isoprivet injections. Moreover, Isoprivet prevented open disease in cats exposed to contacts with FRDC cats. It may be used with success in prophylaxis and therapy in cats with the upper respiratory tract infection, especially in the endemics of FRDC in larger concentrations or breeding farms of cats.
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