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Wplyw preparatu Immunostim-Plus na aktywnosc fagocytarna i metabolizm tlenowy leukocytow krwi szczurow intoksynowanych kadmem

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Wojcik R., Malaczewska J., Jedlinska-Krakowska M., Jakubowski K., Siwicki A. K.

Medycyna Weterynaryjna

2006

tom 62

nr 10

1179-1182

The purpose of the study was to determine the influence of Immunostim-Plus on the phagocyte activity and oxidative metabolism of blood neutrophils and monocytes in rats intoxicated by cadmium. The study was performed on 40 Wistar/Han rats, divided into 4 groups (I-IV), 10 animals in each. Rats from group II were administered Immunostim-Plus in their drinking water at a dose of 3.15 mg/rat/day, rats from group III received cadmium chloride in their drinking water at a dose of 2.1 mg/rat/day, and rats from group IV received cadmium chloride with Immunistim-Plus in similar doses. Rats from group I were administered water only (control group). Following day 50 of the experiment, blood from the rats of each group was taken for immunology examinations. The Phagotest was used to study phagocyte activity and Bursttest was used to study the oxidative metabolism of blood neutrophils and monocytes by flow cytometry. The results indicated that Immunostim-Plus modulated the phagocyte activity and oxidative metabolism of blood neutrophils and monocytes suppressed by cadmium in rats. The study indicated the immuno-restorative activity of Immunostim-Plus

Ograniczanie wyników

1 Medycyna Weterynaryjna

1 Jakubowski K.

1 Jedlinska-Krakowska M.

1 Malaczewska J.

1 Siwicki A. K.

1 Wojcik R.

1 2006

Wyniki wyszukiwania

Wplyw preparatu Immunostim-Plus na aktywnosc fagocytarna i metabolizm tlenowy leukocytow krwi szczurow intoksynowanych kadmem