Two experiments were performed on slaughter cockerel chicks (Astra B2) to establish the influence of probiotics Biogen Dw (periodically applied in drinking water) and Biogen Dp (added to standard mixed feeds at a dose of 0,5 kg/ton), on productional effects (dynamic of growth, index of food conversion, healthy state) and on the following physiological parameters: morphology of peripheral blood, content of serum Ca, P, Mg, uric acid, immunoglobulins, total proteins and electrophoretic protein freactions, activity of microphages (test Chl and NBT), activity of serum enzymes — AspAT, AlAT, AcP, AT and the level of postvaccination immunity against ND, and morphology of internal organs (liver, spleen, kidneys, pancreas, heart, bursa of Fabricius, duodenum and ileum) and carrier state of Salmonella. It was found a positive influence of the used probiotics on dynamic of growth of chickens and on their healthy state. Birds receiving Biofen Dw characterized a higher slaughter body weight by 3.28% and a better index of food conversion by 1.2%. In chickens receiving Biogen Dp these values increased by 3.7—4.4% and 1.7—5.8%, respectively. Blood parameters were not affected. Only a slight increase in parameters of cellular immunity and in postvaccination immunity against ND, and a lack of Salmonella enteritidis carrier state was observed in birds after the used probiotics. The probiotics do not caused significant morphologic changes in the examined internal organs. Increased only the number of follicles in the liver and ileum wall without signs of stimulation.
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