Efficacy of procaine penicillin with streptomycin and oxytetracycline (Terramycin LA, Pfizer) in the treatment of MMA syndrome in sows from small breeding centres was evaluated. In 86.6% of sows treated with penicillin and streptomycin. Positive results were noted, whereas only 26.7 % of sows treated with oxytetracycline reacted positively to the applied therapy (p<0.001). Moreover, 50% of sows reacting negatively to oxytetracycline were cured with penicillin with streptomycin.