The influence of unspecific immunostimulation on the level of haptoglobin (Hp) in the sera of female polar foxes during a reproductive period has been determined. A statistically significant increase of the Hp level in sera of female foxes before immunostimulation resulted from a developing infectious inflammatory process in the reproductive tract. The serum level of Hp in sera of the females stimulated unspeciflcally is close to physiological values. However, in sera of the females from a control group the concentration of Hp persisted on a high level during the entire period of the experiment. The evaluation of the state of health of animals on the basis of the concentration of serum Hp decreases the risk of the transmission of diseases in farms of breeding foxes and hence decreases economical losses. Determining the concentration of Hp in sera of female polar foxes may be a useful criterion for the evaluation of their state of health during the reproduction period and efficacy of the unspecific immunostimulation used.
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