Znaleziono wyników: 3

Liczba wyników na stronie

Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: new mutation

Sortuj według:

Ogranicz wyniki do:

A new SNP in the promoter region of the porcine MYF5 gene has no effect on its transcript level in m.longissimus dorsi

100%

Urbanski P., Flisikowski K., Starzynski R. R., Kuryl J., Kamyczek M.

Journal of Applied Genetics

2006

tom 47

nr 1

Myogenic factor 5 (myf-5) is the product of the MYF5 gene, belonging to the MyoD family. This transcription factor participates in the control of myogenesis. We identified 3 new mutations in the promoter region of the gene: A65C, C580T and C613T. The aim of this study was to evaluate the influence of the A65C transversion on gene expression. The analysis was conducted on 15 Polish Large White gilts. The relative content of MYF5 mRNA in m. longissimus dorsi did not differ significantly across MYF5 genotypes (AA, AC, CC). This result suggests that the A65C transversion may not play an important role in the expression of the MYF5 gene in analysed adult muscle but it abolishes a putative binding site for two transcription factors (CDP and HSF1) and creates such a site for Sp1.

Codon 129 polymorphism of the PRNP gene in normal Polish population and in Creutzfeldt-Jakob disease, and the search for new mutations in PRNP gene

100%

Bratosiewicz J., Liberski P. P., Kulczycki J., Kordek R.

Acta Neurobiologiae Experimentalis

2001

tom 61

nr 3

Screening for mutations affecting sexual reproduction after activation tagging in Arabidopsis thaliana

100%

Perrella G., Cremona G., Consiglio F., Errico A., Bressan R. A., Conicella C.

Journal of Applied Genetics

2006

tom 47

nr 2

In this work, a seed-set-based screening was performed on 70 lines of Arabidopsis thaliana after activation tagging mutagenesis to identify mutations in reproductive mechanisms. Five mutants showed significantly lower seed set than the wild type and confirmed the phenotype in the progeny. This phenotype was linked with the marker gene bar carried by T-DNA conferring glufosinate resistance. Genetic analysis revealed that the mutation inheritance was sporophytic in 3 mutants and gametophytic in 2 mutants. In addition, 2 mutants had an extra T-DNA copy. Thus activation tagging can be an effective strategy to identify new mutations affecting sporogenesis or gametogenesis.

Ograniczanie wyników

2 Journal of Applied Genetics

1 Acta Neurobiologiae Experimentalis

1 Bratosiewicz J.

1 Bressan R. A.

1 Conicella C.

1 Consiglio F.

1 Cremona G.

1 Errico A.

1 Flisikowski K.

1 Kamyczek M.

1 Kordek R.

1 Kulczycki J.

1 Kuryl J.

1 Liberski P. P.

1 Perrella G.

1 Starzynski R. R.

1 Urbanski P.

2 2006

1 2001

Wyniki wyszukiwania

A new SNP in the promoter region of the porcine MYF5 gene has no effect on its transcript level in m.longissimus dorsi

Codon 129 polymorphism of the PRNP gene in normal Polish population and in Creutzfeldt-Jakob disease, and the search for new mutations in PRNP gene

Screening for mutations affecting sexual reproduction after activation tagging in Arabidopsis thaliana