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Histological and histochemical study of the magnocellular neuroendocrine system in white rat after parenteral administration of adrenaline

100%

Arciszewska E., Borowska H., Niklinska W.

Folia Histochemica et Cytobiologica

2001

tom 39

nr 2

The morphological and histochemical neurosecretory magnocellular system in the rat after administration of chlorpromazine

84%

Arciszewska E., Borowska H., Sawicki B.

Folia Morphologica

2004

tom 63

nr 1

The effect of chlorpromazine (CPZ) on the neurosecretory action of the hypothalamo-hypophyseal system was investigated in 72 male rats. The experimental animals received CPZ in a dose of 0.4 mg, 4.0 mg and 20.0 mg/kg b.w. for 30 days. The rats were sacrificed by decapitation at 24 h and 7 days after the last dose of the drug. The neurosecretory material was stained with paraldehyde fuchsin in the supraoptic nucleus, paraventricular nucleus, eminentia mediana and neurohypophysis, the tigroid was stained with toluidine blue and the acid phosphatase activity was evaluated histoenzymatically. It was found that CPZ reduced the content of the neurosecretory material after 24 h, while an increase was observed 7 days after the last drug administration.

Ograniczanie wyników

1 Folia Histochemica et Cytobiologica

1 Folia Morphologica

2 Arciszewska E.

2 Borowska H.

1 Niklinska W.

1 Sawicki B.

1 2004

1 2001

Wyniki wyszukiwania

Histological and histochemical study of the magnocellular neuroendocrine system in white rat after parenteral administration of adrenaline

The morphological and histochemical neurosecretory magnocellular system in the rat after administration of chlorpromazine