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Immunocytochemical analysis of the tissue location of cytokines [IL-2 and IL-12] in neuroendocrine lung cancer

100%

Kasprzak A., Przewozna M., Zabel M., Pankowski J., Surdyk-Zasada J.

Folia Morphologica

2003

tom 62

nr 3

301-303

The study aimed at immunocytochemical evaluation of the cellular expression of two cytokines, IL-2 and IL-12 in lung carcinoids (n = 10), following the earlier demonstration of two markers of endocrine tumours (chromogranin A and NSE — neuron-specific enolase). In the immunocytochemical studies the classical avidin-biotinylated peroxidase (ABC) technique was used. Results of the tests were semiquantitatively appraised employing the IRS scale. In 9/10 cases intense reaction (score: 6–12 points) was noted for both lung neuroendocrine markers. In all cases of carcinoma co-expression of IL-2 and IL-12 was demonstrated in cells of the tumours. The cytokines showed a cytoplasmic localisation of mean (score: 3–4 points) or high (score: 6–12 points) intensity of reaction. Our studies point to a possible role of the two cytokines in the proliferation of lung neuroendocrine carcinomas but more detailed analysis is required on a broader material.

Central nervous system peptide and amino acid modulation of luteinizing hormone and prolactin secretion in the pig

100%

Kraeling R. R., Barb C. R., Leshin L.S, Rampacek G. B.

Journal of Physiology and Pharmacology. Supplement

1992

tom 43

nr 1

The endocrine involvement in lipid metabolism differences in long- and short-winged males of a flightless bug, Pyrrhocoris apterus L. [Heteroptera]

80%

Kodrik D., Socha R., Sula J.

Pestycydy

2005

nr 4

117-123

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Effect of phosphate supplementation on metabolic and neuroendocrine responses to exercise and oral glucose load in obese women during weight reduction

80%

Kaciuba-Uscilko H., Nazar K., Chwalbinska-Moneta J., Ziemba A., Kruk B., Szczepanik J., Titow-Stupnicka E., Bicz B.

Journal of Physiology and Pharmacology

1993

tom 44

nr 4

Ograniczanie wyników

1 Folia Morphologica

1 Journal of Physiology and Pharmacology

1 Journal of Physiology and Pharmacology. Supplement

1 Pestycydy

1 Barb C. R.

1 Bicz B.

1 Chwalbinska-Moneta J.

1 Kaciuba-Uscilko H.

1 Kasprzak A.

1 Kodrik D.

1 Kraeling R. R.

1 Kruk B.

1 Leshin L.S

1 Nazar K.

1 Pankowski J.

1 Przewozna M.

1 Rampacek G. B.

1 Socha R.

1 Sula J.

1 Surdyk-Zasada J.

1 Szczepanik J.

1 Titow-Stupnicka E.

1 Zabel M.

1 Ziemba A.

1 2005

1 2003

1 1993

1 1992

Wyniki wyszukiwania

Immunocytochemical analysis of the tissue location of cytokines [IL-2 and IL-12] in neuroendocrine lung cancer

Central nervous system peptide and amino acid modulation of luteinizing hormone and prolactin secretion in the pig

The endocrine involvement in lipid metabolism differences in long- and short-winged males of a flightless bug, Pyrrhocoris apterus L. [Heteroptera]

Effect of phosphate supplementation on metabolic and neuroendocrine responses to exercise and oral glucose load in obese women during weight reduction