Synthetic pyrethroids commonly used for plant protection often contaminate superficial water sources and therefore they become a health threat for fish. The objective of the studies was to evaluate the influence of permethrin present in water on phagocytic activity of neutrocytes macrophage/monocytes of the main kindneys and circulatory blood of the carp. The fish of about 90 ±10 g were exposed for 96 h to permethrin at a concentration of 0.03 and 1.1 µg/L in the insecticide Ambusz 25EC. The percentage of phagocytic cells (KF) among neutrocytes and macrophages, the value of phagocytic index (IF) and metabolic activity of phagocytes (NBT) were determined in the kidneys and in blood of 6 individuals from each experimental group at 1, 3, 4, 7 and 14 days after the end of the experiment. The same parameters have been evaluated three times for controls at day 1, 7 and 14 of the experiment. The 96-hour exposure of the carp to permethrin during the experiment induced leukopenia and neutrocytosis and lowered the percentage of the kidney cells (KF) active in phagocytosis. Compared to control, at day 7 the value of phagocytic index in the fish under experimentation also decreased.
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