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Ratchets, molecular motors, and noise-induced transport

100%

Luczka J.

Cellular and Molecular Biology Letters

1996

tom 01

nr 3

The Feynman ratchet and pawl machine is presented to illustrate some implications of the Second Law of thermodynamics and to demonstrate how the useful work can be extracted from fluctuations. Molecular motors moving along microtubules and responsible for transporting vesicles, organelles and other substances in cells are described in terms of Brownian ratchets driven by non-equilibrium fluctuations of the ATP cycles. Models of non-thermal fluctuations are presented and used for showing the noise-induced transport phenomena in spatially periodic structures.

Directionality of kinesin motors

100%

Kasprzak A. A., Hajdo L.

Acta Biochimica Polonica

2002

tom 49

nr 4

Kinesins are molecular motors that transport various cargoes along microtubule tracks using energy derived from ATP hydrolysis. Although the motor domains of kinesins are structurally similar, the family contains members that move on microtubules in opposite directions. Recent biochemical and biophysical studies of several kinesins make it possible to identify structural elements responsible for the different directionality, suggesting that reversal of the motor movement can be achieved through small, local changes in the protein structure.

Ograniczanie wyników

1 Acta Biochimica Polonica

1 Cellular and Molecular Biology Letters

1 Hajdo L.

1 Kasprzak A. A.

1 Luczka J.

1 2002

1 1996

Wyniki wyszukiwania

Ratchets, molecular motors, and noise-induced transport

Directionality of kinesin motors