Wyniki wyszukiwania

1

Fluorescence in situ hybridization [FISH] - application in research and diagnostics

100%

Budny B., Kanik M., Latos-Bielenska A.

Folia Histochemica et Cytobiologica

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2002

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tom 40

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nr 2

2

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Chromosomal aberrations in humans induced by benzene

84%

Holeckova B., Piesova E., Sivikova K., Dianovsky J.

Annals of Agricultural and Environmental Medicine

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2004

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tom 11

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nr 2

Adverse effects associated with occupational exposure to benzene have often been reported in humans. It has been shown, that benzene causes chromosomal aberrations, sister chromatid exchanges and micronuclei in lymphocytes of exposed workers. In addition to evidence by conventional cytogenetic methods, the genotoxic effect of benzene has also been proved by a more specific approach based on fluorescence in situ hybridization with DNA probes. In the present paper, the nature of benzene-induced chromosomal aberrations and supposed consequence on human health is reviewed. The new possibilities in chromosomal alterations identification by molecular cytogenetic methods are also presented.

3

Cytogenetic analysis of diploid Brassica species

67%

Hasterok R., Maluszynska J.

Acta Biologica Cracoviensia. Series Botanica

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2000

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tom 42

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nr 1

The chromosomes of Brassica species are small and poorly differentiated, and their identification is extremely difficult using conventional cytogenetic methods. Progress in molecular analysis of Brassica species requires cytogenetic maps of their chromosomes. Chromosome-specific markers are needed to distinguish particular pairs of homologous chromosomes and for karyotyping. In this study, three morphological groups of chromosomes in B. campestris (genome A) and B. oleracea (genome C) and two in B. nigra (genome B) were distinguished by the morphometric features of the chromosomes, based upon arm ratio and absolute length. Using fluorescence in situ hybridization and differential stainings it was possible to establish further markers for five pairs of chromosomes in genome A, three in genome B and two in genome C, and to present idiograms of the chromosomes for three diploid Brassica species. However, for clear identification of all chromosome pairs more cytogenetic markers are needed.

4

Cytogenetic markers of Brassica napus L. chromosomes

59%

Hasterok R., Maluszynska J.

Journal of Applied Genetics

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2000

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tom 41

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nr 1

Ograniczanie wyników

1 Acta Biologica Cracoviensia. Series Botanica

1 Annals of Agricultural and Environmental Medicine

1 Folia Histochemica et Cytobiologica

1 Journal of Applied Genetics

2 Hasterok R.

2 Maluszynska J.

1 Budny B.

1 Dianovsky J.

1 Holeckova B.

1 Kanik M.

1 Latos-Bielenska A.

1 Piesova E.

1 Sivikova K.

1 2004

1 2002

2 2000

Fluorescence in situ hybridization [FISH] - application in research and diagnostics

Chromosomal aberrations in humans induced by benzene

Cytogenetic analysis of diploid Brassica species

Cytogenetic markers of Brassica napus L. chromosomes