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Direct and maternal additive genetic variances as well as covariances between these effects were estimated via derivative-free restricted maximum likelihood algorithm under an animal model. 2750 half-bred mares from four Studs were recorded. The following three traits were analysed: height of wither, circumference of chest, circumference of canon. The breed group, year of birth and place of birth were included as fixed effects. The computations were performed using two genetic models (with and without maternal effects). Direct additive heritability estimates were 0.539 for height of wither, 0.345 (and 0.442 from maternal model) for circumference of chest and 0.233 for circumference of cannon. Using the likelihood ratio test it was concluded that the maternal effects were significiant for the analysed traits. Generally, negative correlation estimates between direct and maternal genetic effects were found for single traits.
Selection, one of the more important stages in fur animal breeding, is based on the phenotype of the animals only. Although a phenotype-based evaluation is the quickest and the simplest method that can be carried out in an on-farm environment, the results of such an evaluation, however, remain reliable exclusively in relation to highly heritable traits. The material comprised data collected from the breeding documentation of a standard mink reproduction farm and referred to 12 generations of animals. The covariance components of reproduction and conformation traits were estimated by means of the REML method based on a multitrait animal model, using the DMU software package. The components were used for a BLUP-based estimation of the breeding value of the animals. The genetic trends considerably differed from the phenotypic ones.
Administration intraperitoneally of the Ascaris suum extract - ASE-(0.6-1.4 g of Ascaris proteins/kg/day) at a late stage of organogenesis (8-12 days of gestation) disturbed course of mouse pregnancy. lt has been found that injections of higher doses of ASE to pregnant mice caused the symptoms manifesting maternal toxicity (decreased body weight gain /p < 0.001/ as compared to control, intrauterine resorption of litter, vaginal hemorrhages, female mortality and altered behaviour). There is a linear interrelationship between the logarithm of the dose of ASE and mortality of pregnant mice. The DL₅₀ value of Ascaris proteins for pregnant mice was 1.02 g/kg/day (confidence interval 0.97-1.07 g/kg/day). ASE exerted embryotoxic effects: significantly decreased the number of surviving fetuses per litter and the mean body weight of fetuses, increased the number of fetal resorptions.
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