Wyniki wyszukiwania

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Platelet-activating factor changes in phospholipid extracts from the plasma, peripheral blood mononuclear cells and bone marrow mononuclear cells of patients with acute leukemia - A 31P MRS in vitro study

100%

Kuliszkiewicz-Janus M., Tuz M. A., Kielbinski M., Baczynski S., Jazwiec B., Sladowska H.

Cellular and Molecular Biology Letters

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2008

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tom 13

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nr 1

58-66

The aim of this investigation was to evaluate the changes in PAF concentrations in the plasma, PBMC and BMMC of patients with acute lymphoblastic leukemia (ALL) and acute myeloblastic leukemia (AML). The plasma was from 23 healthy volunteers (HV) and 44 patients with AL (16 ALL, 28 AML). The PBMC were from 15 HV and 55 patients with AL (18 ALL, 37 AML), and the BMMC from 40 patients with AL (11 ALL, 29 AML). Methanol-chloroform phospholipid extraction from 60 × 106 cells (PBMC or BMMC) was performed according to a modified version of Folch’s method. 31P MRS data was obtained on an AMX 300 Bruker spectrometer (7.05 T). The PAF concentration in the plasma of the patients with ALL or AML was lower than that for the healthy volunteers. The PAF concentration in the plasma of the patients with ALL did not differ significantly from that of the patients with AML. In the case of both the PBMC and BMMC, the PAF concentration was significantly diminished in patients with ALL relative to the concentration for those with AML and for the healthy volunteers. No differences were observed in the PAF concentrations for the AML patients and the healthy volunteers.

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Metabolic profiling of Echinostoma caproni and Schistosoma mansoni in their definitive and intermediate hosts

100%

O’Sullivan C., Fried B., Sherma J.

Acta Parasitologica

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2013

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tom 58

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nr 1

This review examines metabolic profiling of Schistosoma mansoni and Echinostoma caproni in their definitive and intermediate hosts. The earlier coverage of the literature on metabolic profiling was reviewed by Wang et al. 2010, Advances in Parasitology, 73, 373–404 and covered mainly studies using proton nuclear magnetic resonance spectroscopy. The methods focused upon in our review are mainly chromatographic. In the studies reviewed, various metabolites were analyzed in hosts infected with either E. caproni or S. mansoni and compared to the uninfected controls.

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P MRS analysis of the phospholipid composition of normal human peripheral blood mononuclear cells [PBMC]

100%

Kuliszkiewicz-Janus M., Tuz M. A., Baczynski S., Prajs I., Jazwiec B.

Cellular and Molecular Biology Letters

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2005

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tom 10

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nr 3

Ograniczanie wyników

2 Cellular and Molecular Biology Letters

1 Acta Parasitologica

2 Baczynski S.

2 Jazwiec B.

2 Kuliszkiewicz-Janus M.

2 Tuz M. A.

1 Fried B.

1 Kielbinski M.

1 O’Sullivan C.

1 Prajs I.

1 Sherma J.

1 Sladowska H.

1 2013

1 2008

1 2005

Platelet-activating factor changes in phospholipid extracts from the plasma, peripheral blood mononuclear cells and bone marrow mononuclear cells of patients with acute leukemia - A 31P MRS in vitro study

Metabolic profiling of Echinostoma caproni and Schistosoma mansoni in their definitive and intermediate hosts

P MRS analysis of the phospholipid composition of normal human peripheral blood mononuclear cells [PBMC]