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1

CD44 as a prognostic factor in laryngeal cancer

100%
Woinska-Rojecka T., Chodynicki S., Chyczewski L., Rzewnicki I.
Folia Histochemica et Cytobiologica. Supplement
|
2001
|
tom 39
|
nr 1
2

Assessment of the ability of mononuclear blood cells to produce IFN-gamma in patients with the laryngeal cancer

86%
Lazarczyk B., Moniuszko T., Kosztyla-Hojna B., Lachowicz M., Rogowski M.
Folia Histochemica et Cytobiologica. Supplement
|
2001
|
tom 39
|
nr 1
3
Content available remote

Gene expression profile analysis in laryngeal cancer by high-density oligonucleotide microanalysis

72%
Markowski J., Oczko-Wojciechowska M., Gierek T., Jarzab M., Paluch J., Kowalska M., Wygoda Z., Pfeifer A., Tyszkiewicz T., Jarzab B., Niedzielska I., Borgiel-Marek H.
Journal of Physiology and Pharmacology. Supplement
|
2009
|
tom 60
|
nr 1
57-63
The assessment of gene expression profile in laryngeal cancer shall allow to implement molecular biology methods in diagnostics, as well as in prognosis of the course of disease. Thus, it may influence the choice of the most optimal decisions in regards to the method of treatment, extent of surgical procedure, or the necessity of adding post-operative radiotherapy. The aim of the project was to analyse the gene expression profile of laryngeal cancer using oligonucleotide microarrays, aiming to derive novel molecular markers for that carcinoma. The study comprised a group of 14 patients (12 males and 2 females) with squamous cell laryngeal carcinoma, diagnosed and surgically treated between 2005 – 2007 in the ENT Department of the Silesian Medical University in Katowice, Poland. RNA was isolated from frozen tissue fragments. To assess gene expression profile, high density oligonucleotide microarrays (Affymetrix U 133 Plus 2.0) were applied, with over 54 thousand probesets for over 47 thousand transcripts. Four genes, previously not assesed in diagnostic context in laryngeal carcinoma, seemed to be valuable markers of that neoplasm. These are: metalloproteinase ADAM12, cycline-dependent kinase 2 - CDK2, kinesine 14 - KIF14, suppressor 1 of checkpoint - CHES1.
4

Expression of CD200 and CD200R regulatory molecules on the CD83plus monocyte-derived dendritic cells generated from patients with laryngeal cancer

72%
Klatka J., Grywalska E., Klatka M., Rahnama M., Polak A., Rolinski J.
Folia Histochemica et Cytobiologica
|
2013
|
tom 51
|
nr 1
5

In vitro evaluation of electroporated gold nanoparticles and extremely-low frequency electromagnetic field anticancer activity against Hep-2 laryngeal cancer cells

72%
Alshehri M. A., Wierzbicki P. M., Kaboo H. F., Nasr M. S. M., Amer M. E., Abuamara T. M. M., Badr D. A., Saleh K. A., Fazary A. E., Mohamed A. F.
Folia Histochemica et Cytobiologica
|
2019
|
tom 57
|
nr 4
6

Correlation between epidemiological, clinical and pathological features and HPV 16 infection in patients with laryngeal squamous cell carcinoma

72%
Morshed K., Polz-Dacewicz M., Szymanski M., Polz D., Trojanowski P., Abushammalah R., Smolen A.
Bulletin of the Veterinary Institute in Puławy
|
2009
|
tom 53
|
nr 1
17-20
HPV DNA was amplified by the nested-PCR method to identify E6/E7 HPV 16 from 72 deep-frozen (-70°C) specimens of LSCC tumours collected after a total laryngectomy. HPV was identified in 38.9% of the specimens. There was no statistically significant correlation between the presence of HPV and epidemiological, clinical, and pathological features, and recurrence. There was no statistically significant correlation between the presence of HPV and survival. HPV infection is not likely to influence survival rates as an independent prognostic factor in patients with laryngeal cancer. The presence of HPV infection in 38.9% of the cases suggest a possible role in the aetiology of laryngeal cancer and support the role of high-risk types of HPV 16 in LSCC.
7

Tumor infiltrating lymphocytes in HLA plus and HLA minus laryngeal cancer - quantitative approach

72%
Dworacki G., Kruk-Zagajewska A., Jezewska E., Sikora J., Zeromski J.
Archivum Immunologiae et Therapiae Experimentalis
|
1999
|
tom 47
|
nr 3
8

Usefulness and efficiency of formalin-fixed paraffin-embedded specimens from laryngeal squamous cell carcinoma in HPV detection by IHC and PCR/DEIA

58%
Morshed K., Polz-Dacewicz M., Szymanski M., Smolen A.
Folia Histochemica et Cytobiologica
|
2010
|
tom 48
|
nr 3
9

Effect of human papillomavirus on cell cycle-related proteins p16INK4A, p21waf1/cip1, p53 and cyclin D1 in sinonasal inverted papilloma and laryngeal carcinoma. An in situ hybridization study

58%
Stasikowska-Kanicka O., Wągrowska-Danilewicz M., Danilewicz M.
Folia Histochemica et Cytobiologica
|
2011
|
tom 49
|
nr 1
10

Loss of heterozygosity for Rb locus and pRb immunostaining in laryngeal cancer: a clinicopathologic, molecular and immunohistochemical study

58%
Pietruszewska W., Klatka J., Borzecki A., Rieske P.
Folia Histochemica et Cytobiologica
|
2008
|
tom 46
|
nr 4
479-485
11

Effects of smoking and diet on selenium concentration in serum and tissue in laryngeal cancer

58%
Borawska M. H., Czyzewska E., Luczaj J., Chodynicki S., Markiewicz R., Soroczynska J.
Żywienie Człowieka i Metabolizm
|
2003
|
tom 30
|
nr 3-4
Aim: Selenium (Se) is of fundamental importance to health conditions. Also, the concentration of Se in human organism depends on dietary intakes. The aim of this study was to analyze the influence of dietary preferences on serum and tissue levels of Se in patients with laryngeal cancer. Methods: Twenty eight patients who had undergone an operation on laryngeal cancer, were studied. Food frequency questionnaires were implemented to collect the dietary> data Serum and tissue levels of Se were determined using atomic absorption spectrometry. Results: In patients with laryngeal cancer the mean Se concentration in serum (38.73±13.9 µg/L) and cancer tissue (94.00± 92.7 ng/g) were significantly lower than in controls (52.56 ±12.8 µg/L and 174.01±120.9 ng/g, accordingly). Smoking and using butter on bread decreased Se levels in tissue of cancer sufferers. Frequent consumption of pork-butcher 's meat increased of Se concentration in serum and cancer tissue, but honey only in serum. Conclusion: Se levels in patients with laryngeal cancer may depend not only on the health condition, but also on the habit of eating pork-butcher 's meat, butter and honey. It can also depend on the fact if a patient smokes or not.
12

The correlation of p53 protein with PCNA at the ultrastructural level in patients with laryngeal squamous cell carcinoma estimated by gold method

58%
Grzanka A., Sujkowska R., Janiak A., Adamska M.
Zeszyty Naukowe Akademii Bydgoskiej. Studia Przyrodnicze
|
2001
|
tom 15
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