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Molekularne aspekty interakcji plemnika z oocytem u ssaków

100%

Kempisty B., Bukowska D., Wozna M., Sikora J., Jaskowski J. M.

Medycyna Weterynaryjna

2010

tom 66

nr 08

s.544-546,bibliogr.

The process of spermegg fusion is one of the most important mechanisms involved in successful fertilization. Studies conducted in an effort to elucidate this process are mainly focused on analyzing the interaction between the membrane proteins of male and female gametes. In the last few years, the genes coding proteins which may play an integral role in the process of sperm-egg binding and fusion have been identified. It has been suggested that sperm ADAMs family proteins are involved in this process. The sperm specific fertilin α, fertilin β and cyritestin are among this protein family. The oocyte’s integrins, which are included in egg cell membrane, form receptors specific for those proteins. The other group of proteins, which are connected with sperm-egg fusion, are specific for oocyte CD9 protein and sperm epididymal protein DE. The aim of this review was to present the characteristics of several proteins involved in the sperm-egg interaction process. The exploration of fertilization mechanisms may become the basic element that will improve assisted reproductive techniques and in vitro fertilization in mammals.

Wybrane aspekty komórkowych mechanizmów regulujących interakcję plamnika i komórki jajowej u ssaków

80%

Bukowska D., Kempisty B., Zaorska K., Antosik P., Pawlowska J., Nowicki M.

Medycyna Weterynaryjna

2014

tom 70

nr 05

Fertilization is a complex process which includes the recognition and fusion of an oocyte and a sperm and the development of a zygote that contains a double set of chromosomes. Each step in this process is precisely controlled at the molecular level in a cascade of biochemical reactions (cortical and acrosome reactions) that determine the future of both gametes. Biochemical reactions not only reorganize gametes in morphological, physiological, and biochemical terms, but also prepare them for the future coordinated communication. Molecular aspects of gamete development and fertilization include the reorganization of the cell membrane and ligand-receptor reactions that affect the recognition of gametes and lead to the formation of pronuclei and zygote development. This article discusses several aspects of the recognition, interaction, and fusion of a sperm and an oocyte. It also describes biochemical reactions involved in the development of gametes that are capable of fertilization.

Ograniczanie wyników

2 Medycyna Weterynaryjna

2 Bukowska D.

2 Kempisty B.

1 Antosik P.

1 Jaskowski J. M.

1 Nowicki M.

1 Pawlowska J.

1 Sikora J.

1 Wozna M.

1 Zaorska K.

1 2014

1 2010

Wyniki wyszukiwania

Molekularne aspekty interakcji plemnika z oocytem u ssaków

Wybrane aspekty komórkowych mechanizmów regulujących interakcję plamnika i komórki jajowej u ssaków