Wyniki wyszukiwania

1

Molecular mechanism of the apoptotic cell death of glioma cells induced by immunosuppressive drug - cyclosporin A

100%

Kaminska B.

Folia Histochemica et Cytobiologica. Supplement

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1997

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tom 35

|

nr 2

2

Interleukin 7 receptor alpha as a potential therapeutic target in transplantation

86%

Racape M., Vanhove B., Soulillou J.-P., Brouard S.

Archivum Immunologiae et Therapiae Experimentalis

|

2009

|

tom 57

|

nr 4

253-261

3

Alterations in brain development in rats treated with immunosuppresant drugs Sandimmune and Prograf and their vehicle components

86%

Uram L., Gzielo-Jurek K., Janeczko K., Kielbinski M., Setkowicz Z.

Acta Neurobiologiae Experimentalis

|

2013

|

tom 73

|

nr 1

Cyclosporin A and tacrolimus are powerful immunosuppressants used as post-operation medication after allogenic transplantations. Unfortunately, the drugs Sandimmune (cyclosporin A) and Prograf (tacrolimus) exhibit negative side effects. These side effects may be linked not only to the active ingredients themselves, but also to the vehicle used for their delivery – Cremophor EL and/or ethanol. Sandimmune, Prograf, ethanol, Cremophor EL or Cremophor EL with ethanol (i.e. the complete vehicle) in a saline solution were administered to male Wistar rats either on 6th and 7th or 30th and 31st day postnatally. The functional changes in the nervous system elicited by these substances were assessed by observing the intensity of seizures induced by a single i.p. injection of pilocarpine at 60th postnatal day. Brain anatomy was also analyzed by comparing brain mass, lateral ventricle relative area, thickness of cerebral hemisphere wall, relative size of the hippocampus as well as total density of cresyl violet-stained neurons in the cerebral hemisphere walls between control and experimental animals. Our data point to a significant effect of all tested substances on central nervous system development. The greatest effects on seizure severity and brain structure were associated with the complete vehicle. Such effects (although less sever) were also observed for Cremophor EL and ethanol given separately.

4

Limitations of cyclosporine toxicity assessment in early stage after renal transplantation

86%

Marchewka Z., Kuzniar J., Dlugosz A., Krasnowski R., Zynek-Litwin M., Stoklosa A., Klinger M.

Acta Toxicologica

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2007

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tom 15

|

nr 1

5

Therapeutic potential of induced and natural FoxP3plus regulatory T cells for the treatment of graft-versus-host disease

72%

Prinz I., Koenecke C.

Archivum Immunologiae et Therapiae Experimentalis

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2012

|

tom 60

|

nr 3

6

Suppressor properties of human CD8+CD28− T cells in mixed leukocyte reaction are not affected by CsA and RAPA

72%

Korecka-Polak A., Bocian K., Pachowka M., Jalbrzykowska A., Korczak-Kowalska G.

Archivum Immunologiae et Therapiae Experimentalis

|

2016

|

tom 64

|

nr 5

7

Lymphocyte phenotyping of renal transplanted patients under two different immunosuppressive protocols

72%

Tzanno-Martins C., Araujo P., Orii N., Duarte A. J. S., Paula F. J., Duley J. A., Nahas W., Arap S., Ianhez L. E., Chocair P. R.

Cellular and Molecular Biology Letters

|

1999

|

tom 04

|

nr 3

8

Exhaled nitric oxide concentration in patients after heart transplantation

58%

Nadziakiewicz P., Knapik P., Zakliczynski M., Zembala M., Urbanska E., Pacholewicz J.

Journal of Physiology and Pharmacology. Supplement

|

2007

|

tom 58

|

nr 5

9

In vitro analysis of the mode of action of the immunosuppressive drug 15-deoxyspergualin

58%

Waaga A. M., Krzymanski M., Ulrichs K., Treumer J., Oko A., Muller-Ruchholtz W.

Archivum Immunologiae et Therapiae Experimentalis

|

1996

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tom 44

|

nr 2-3

10

Hematological effects of the new immunosuppressive drug 15-deoxyspergualin

58%

Waaga A. M., Krzymanski M., Ulrichs K., Wierusz-Wysocka B., Muller-Ruchholtz W.

Archivum Immunologiae et Therapiae Experimentalis

|

1993

|

tom 41

|

nr 2

Ograniczanie wyników

Molecular mechanism of the apoptotic cell death of glioma cells induced by immunosuppressive drug - cyclosporin A

Interleukin 7 receptor alpha as a potential therapeutic target in transplantation

Alterations in brain development in rats treated with immunosuppresant drugs Sandimmune and Prograf and their vehicle components

Limitations of cyclosporine toxicity assessment in early stage after renal transplantation

Therapeutic potential of induced and natural FoxP3plus regulatory T cells for the treatment of graft-versus-host disease

Suppressor properties of human CD8+CD28− T cells in mixed leukocyte reaction are not affected by CsA and RAPA

Lymphocyte phenotyping of renal transplanted patients under two different immunosuppressive protocols

Exhaled nitric oxide concentration in patients after heart transplantation

In vitro analysis of the mode of action of the immunosuppressive drug 15-deoxyspergualin

Hematological effects of the new immunosuppressive drug 15-deoxyspergualin