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  1. 5 Journal of Physiology and Pharmacology

  2. 2 Annals of Agricultural and Environmental Medicine

  3. 2 Folia Morphologica

  4. 2 Journal of Physiology and Pharmacology. Supplement

  5. 2 Medycyna Weterynaryjna

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  1. 3 Kaleczyc J.

  2. 3 Lakomy M.

  3. 3 Sienkiewicz W.

  4. 2 Arruebo M. P.

  5. 2 Damanhouri Z. A.

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  1. 1 2019

  2. 1 2013

  3. 1 2011

  4. 1 2010

  5. 3 2009

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1
Content available remote

The myoelectric activity of ileum in fasted and fed young pigs

100%
Romanski K. W., Rudnicki J., Slawuta P.
Journal of Physiology and Pharmacology
|
2001
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tom 52
|
nr 4,2
To precise the character of myoelectric activity of distal small intestine, in 8 young pigs 1 bipolar electrode was attached at the serosal side of the jejunum and 7 electrodes were sutured at terminal ileum. After the recovery, the animals were fed twice daily during at least 2 weeks and were fasted 24 h before each experiment. Myoelectric activity was recorded with electroencephalograph throughout the experiment lasting 3—5 h. After control recording the standard food was given during the end of ileal phase 1 of migrating myoelectric complex (MMC) and registration of myoelectric activity was continued. Ileal propagated or non-propagated minute rhythm was observed in 64% of the experiments performed, during phase 2b of MMC. In most animals studied, the long isolated spike burst series lasting 1—6 min and short isolated spike burst series lasting 15—25 s were observed. Feeding induced myoelectric activity in the jejunum usually after 1—2 min and, in the ileum, during most episodes, after 2—9 min, for 4—10 min. During and after feeding, the short-lasting “transient fed pattern“ was observed. Mean propagation velocity of phase 3 MMC was 4.4 ± 0.8 and 8.1 ± 0.6 cm/min (mean ± S.E.M., p > 0.05) before and after feeding, respectively. Phase 3 MMC was preceded by 2—3 spike burst series lasting 40—70 s each before feeding and 1—3 min after feeding. Single propagated spike bursts arrived more frequently after feeding. Two types of minute rhythm, propagated and stationary, were observed. Giant spike bursts, propagated contractions and ultrarapid spike rushes were recorded occasionally. In conclusion, the myoelectric activity of terminal ileum in swine is eventful, exhibits wide range of irregularity and its response to feeding is relatively weak and delayed as compared to the upper small intestine.
2

The effect of jejunoectomy on alkaline phosphatase activity in the ileum

86%
Gawlik Z., Nutzenadel W., Krawczyk M., Wiśniewska I. E.
Folia Histochemica et Cytobiologica
|
1985
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tom 23
|
nr 3
3
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Content available

Characterization of the heat-released substance from rat ileal muscle

86%
Damanhouri Z. A., Tayeb O. S.
Annals of Agricultural and Environmental Medicine
|
1999
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tom 06
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nr 2
4
Content available remote

Polyviewed expression of the altered contractility of the guinea-pig ileum after ischemia in situ and superfusion in vitro

86%
Santiago-Mejia J., Ventura-Martinez R., Gomez C., Parra-Gamez L., Gonzalez-Rios J., Rodriguez R.
Journal of Physiology and Pharmacology
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2007
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tom 58
|
nr 2
This study deals with the polyviewed expression of the altered contractility of the isolated ileum of the guinea-pig after ischemia/superfusion (I/S). Intestinal ischemia was produced by clamping the superior mesenteric artery for 40, 80 or 160 min. Ischemic and non-ischemic segments taken from the same guinea-pig were mounted for tension recording in organ baths and superfused (120 min) with an oxygenated Krebs-bicarbonate solution. Data were analyzed by means of the Polyview System software, which allows detecting simultaneously several events of one response. Histopathological changes in myenteric neurons were also examined. We found that ischemia in situ followed by superfusion in vitro (reoxygenation) severely reduces the spontaneous intestine contractile activity, and significantly decreases the maximal contractile response to ACh and to electrical field stimulation (EFS), the maximal rate of tension, and the sensitivity of the tissue to EFS. In addition, these ischemic intestines respond with a long-lasting contracture when electrical stimulation was started at supramaximal voltage. Functional alterations were time dependent. Neurons exhibited features of necrosis. These results provide clear evidence of detrimental effects of I/S on intestine contractile function. Digital analysis allows quantification of additional parameters important for evaluation of functional changes after I/S and of the degree of neuroprotection.
5

Arterial vascularization of the terminal ileum in human fetuses

86%
Pitynski K., Skawina A., Gorczyca J., Budzyn M.
Folia Morphologica
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1995
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tom 54
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nr 3
6

Further evidence on the release of a heat released substance from isolated rat ileum and diaphragm

86%
Damanhouri Z. A., Tayeb O. S.
Annals of Agricultural and Environmental Medicine
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1994
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tom 01
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nr 1
7

The influence of inflammation on the expression of neuropeptides in the ileum-projecting primary sensory neurones in the pig

72%
Pidsudko Z., Wasowicz K., Sienkiewicz W., Kaleczyc J., Czaja K., Lakomy M.
Folia Morphologica
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2003
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tom 62
|
nr 3
235-237
In the present study the ELISA test was used to investigate the influence of chemically-induced ileitis on the dorsal root ganglia (DRG) neurons in the pig. The preliminary retrograde fluorescent tracing study revealed that ileum-projecting sensory neurones (IPN) are located in the thoracic ganglia (Th; Th₈–Th₁₃). The ileum wall in experimental (E) pigs was subjected to multiple injection with 4% paraformaldehyde to induce inflammation, while in the control (C) animals the organ was injected with 0.1 M phosphate buffer. Three days later the DRGs (Th₈–Th₁₃) collected from all the animals were evaluated for VIP, SP, CGRP, NPY, GAL and SOM content with an ELISA test. It was found that the inflammation increased clearly the tissue level of SP, GAL and SOM.
8
Content available remote

The role of Ca2plus in the contractility of rabbit small intestine in vitro

72%
Grasa L., Rebollar E., Arruebo M. P., Plaza M. A., Murillo M. D.
Journal of Physiology and Pharmacology
|
2004
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tom 55
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nr 3
This study evaluated the role of Ca2+ in spontaneous and ACh- and KCl-induced contractions in longitudinal and circular smooth muscle from rabbit small intestine in vitro. In the first experiment, the amplitude, frequency and tone of spontaneous contractions in longitudinal and circular smooth muscle of small intestine were determined and, in the second experiment, the ACh- and KCl-induced responses of longitudinal and circular smooth muscle were measured. Atropine and guanethidine reduced the amplitude and tone of contractions in longitudinal and circular muscle, but reduced the frequency of contractions in circular muscle, only. TTX attenuated the amplitude of contractions and decreased the tone of contractions in longitudinal muscle, but increased the tone in circular muscle. Ca2+-free solutions, verapamil, nifedipine and caffeine diminished the three parameters of spontaneous contractions. Thapsigargin and cyclopiazonic acid increased the amplitude and tone of contractions in ileum longitudinal muscle, only, and cyclopiazonic acid increased the amplitude of contractions in circular muscle. Ca2+-free solutions, verapamil, nifedipine, thapsigargin, cyclopiazonic acid, and caffeine diminished ACh- and KCl-induced contractions. Those results suggest that extracellular Ca2+ plays a role in spontaneous contractions, and extracellular and intracellular Ca2+ participate in the ACh- and KCl-induced contractions of rabbit small intestine.
9

Calcitonin increases the inhibitory effect of opioid agonist in guinea-pig ileum

72%
Borowicz B., Sagan M., Korzeniowska A.
Journal of Physiology and Pharmacology. Supplement
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2001
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tom 52
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nr 2
10

The distribution and chemical coding of neurons in the celiac-superior mesenteric ganglion complex supplying the normal and inflamed ileum in the pig

72%
Kaleczyc J., Pidsudko Z., Franke-Radowiecka A., Sienkiewicz W., Majewski M., Lakomy M., Timmermans J. P.
Polish Journal of Veterinary Sciences
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2004
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tom 07
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nr 3
The present study investigated the chemical coding of neurons in the celiac-superior mesenteric ganglion complex supplying the normal (n = 4) and inflamed (n=4) ileum (chemically-in- duced inflammation) in juvenile pigs using retrograde tracing combined with immunohistochem- istry. Ileum-projecting neurons (IPN) were predominantly distributed in the left and right superior mesenteric pools of the ganglion. The majority of them were adrenergic (tyrosine hydroxylase-positive) and also contained neuropeptide Y, somatostatin or galanin. No clear-cut differences in the distribution and chemical coding of IPN were found between normal and inflamed pigs. However, in the inflamed group, the density of peptidergic, IPN-associated nerve fibres was higher than that found in the control group.
11
Content available remote

Corticotropin releasing factor signaling in colon and ileum: regulation by stress and pathophysiological implications

58%
Larauche M., Kiank C., Tache Y.
Journal of Physiology and Pharmacology. Supplement
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2009
|
tom 60
|
nr 7
12

Morphology and morphometric analysis of selected elements of digestive tract in great cormorant Phalacrocorax carbo sinensis

58%
Dziala-Szczepanczyk E., Wilczynska I.
Electronic Journal of Polish Agricultural Universities. Series Biology
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2010
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tom 13
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nr 4
13

Determination of spasmolytic and antispasmodic activities of thyme extracts and one of their major components, rosmarinic acid, in isolated rabbit ileum and isolated rat aorta

58%
Bazylko A., Zygmunt M., Sapa J., Strzelecka H., Filipek B.
Acta Biologica Cracoviensia. Series Zoologia
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2009
|
tom 51
49-54
14

Influence of low doses of deoxynivalenol on histopathology of selected organs of pigs

58%
Zielonka L., Wisniewska M., Gajecka M., Obremski K., Gajecki M.
Polish Journal of Veterinary Sciences
|
2009
|
tom 12
|
nr 1
Deoxynivalenol is one of mycotoxins that are most frequently determined in animal feed manufactured in Poland. The examination of histopathological lesions concomitant with deoxynivalenol intoxication is difficult because of the common, often synergistic, reaction of this mycotoxin with other toxins, such as zearalenone or ochratoxin A, which has a strong nephrotoxic activity. The possibility of estimating histopathological lesions in the course of intoxication with pure toxin at various doses is therefore of interest. Dosages used in this experiment relate to clinical cases observed in feeding the animals with whole ration feed obtained by processing feedingstuffs contaminated with Fusarium moulds. However, concerning the fact of one-shot administration of clinically pure toxin, the main question was if it was a sufficient dose to cause changes in the histopathological picture of gastrointestinal tract organs. The experiment was carried out on 12 nursery pigs of mixed breed (Polish White Large x Polish White Ear-pendent) with an average body weigh of 35 kg. The experimental nursery pigs were divided into 3 groups: group I (n=4) – control; group II (n=4) – DON administered at a dose of 0.2 mg/kg b.w.; group III (n=4) – DON administered at a dose of 0.4 mg/kg b.w. After slaughter of the animals, macroscopic examination was performed and segments of duodenum, jejunum, ileum, liver and mesenteric lymph nodes were sampled and assigned for histopathological examination. The results obtained equate to the clinically observed signs in swine production involving some nutrient metabolism disturbances in the gastrointestinal tract in the course of deoxynivalenol mycotoxicosis. Histopathological examination of segments of the duodenum, the jejunum, the ileum, the liver and the lymph nodes indicate that the regressive lesions are more expressed in the experimental group treated with the highest concentration of deoxynivalenol.
15

Effect of dietary supplementation with extracts of rosemary, olive leaves, pine bark and quercetin on selected performance indices of broiler chickens and microbiological status of their ileum

58%
Sierzant K., Orda J., Korzeniowska M., Malicki A.
Medycyna Weterynaryjna
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2019
|
tom 75
|
nr 04
A total of 180 1-day-old male Hubbard Flex broiler chickens were used in a 32-day model experiment to determine the effects of dietary supplementation with quercetin (Q) and with polyphenolic extracts of rosemary (RO), olive leaves (OL) and pine bark (PB) on the performance of the birds and the microbiological status of their ileum. The chickens were randomly allocated into 9 groups: the control group (with 6 replicates, 6 birds per cage) and 8 treatment groups (with 3 replicates in each, 6 birds per cage), and fed ad libitum throughout the experimental period with a basal isoenergetic and isoprotein control diet or with the same basal diet containing two concentrations of RO, OL and PB extracts (2.50 and 5.00 g/kg), and Q (0.25 and 0.50 g/kg). The body weight gain (BWG) and the feed conversion ratio (FCR) were determined during the experiment. At day 32, two randomly selected birds from each cage were slaughtered, and 5-centimetre-long pieces of the ileum beginning from the Meckel's diverticulum were collected to analyze the number of microorganisms in the intestinal content. Chickens’ weight gain and FCR were not affected by the OL-, PB- and Q-enriched diets, but supplementation with RO significantly (P < 0.05) impaired FCR. BWG was significantly (P < 0.05) reduced when chickens were fed with mixtures containing 2.50 and 0.25 g/kg of the polyphenolic additives. The number of CFUs of intestinal microorganisms was not significantly affected (P > 0.05) by the diet modification. However, a large decrease (P > 0.05) was observed in the CFUs of coliform bacteria (up to 96%), E. coli (up to 93%), Lactobacillus spp. (up to 89%), molds and yeasts (up to 95%) and anaerobic Clostridium spp. (up to 52%) in the ileum content of chickens supplemented with the additives containing polyphenols.
16

Severe intestinal coccidiosis in a newborn lion [Panthera leo]

58%
Dubey J. P., Jardine J. E.
Acta Protozoologica
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2008
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tom 47
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nr 1
63-68
17

Neuropeptide-immunoreactive nerve structures in the ileum and large intestine of pigs undergoing dysentery

58%
Sienkiewicz W., Wasowicz K., Kaleczyc J., Lakomy M.
Medycyna Weterynaryjna
|
2006
|
tom 62
|
nr 10
1127-1133
The aim of the study was to investigate the expression of biologically active substances in intramural neurons supplying the ileum and large intestines (caecum, spiral colon and descending colon) in normal (control) pigs and in pigs suffering from dysentery. Higher numbers of galanin (GAL)-, vasoactive intestinal polypeptide (VIP)- and calcitonin gene-related peptide (CGRP)-immunoreactive (-IR) neuronal somata were found in the myenteric (MP), and outer (OSP) and inner submucus (ISP) intestinal nerve plexuses in dysenteric pigs as compared to control animals. Additionally, the density of substance P (SP)- and VIP-IR nerve fibres in the studied tissues was higher in dysenteric than in controls animals, whereas the number of CGRP-IR nerve fibres remained unchanged, or even was lower in the experimental pigs. The number of SP-IR nerve cell bodies in the MP of all intestinal segments studied was comparable in dysenteric and control pigs. An increased number of SP-IR perikarya were observed in OSP and ISP of the ileum, cecum and centripetal turns; whereas the number of SP-IR somata was lower in the plexuses of centrifugal turns and the descending colon. The number of nerve fibres found in all layers of the intestinal wall was lower in dysenteric pigs. Each of the intramural plexuses in all the intestinal segments studied contained less than 1% of neuropeptide Y (NPY)-IR neurones and this characteristic was similar both in dysenteric and control pigs. The number of NPY-IR nerve fibres increased slightly in the plexuses as well as in both muscular layers and mucosa.
18

Effects of dietary caprylic and capric acids on piglet performance and mucosal epithelium structure of the ileum

58%
Hanczakowska E., Szewczyk A., Okon K.
Journal of Animal and Feed Sciences
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2011
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tom 20
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nr 4
19

Composed influences of the amphibian cholecystokinin analogue - cerulein administered during various phases of the migrating myoelectric complex on duodenal, jejunal and ileal myoelectric activity in sheep

58%
Romanski K. W.
Bulletin of the Veterinary Institute in Puławy
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2006
|
tom 50
|
nr 2
20
Content available remote

The role of NO in the contractility of rabbit small intestine in vitro: effect of K+ channels

58%
Grasa L., Rebollar E., Arruebo M. P., Plaza M. A., Murillo M. D.
Journal of Physiology and Pharmacology
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2005
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tom 56
|
nr 3
Nitric oxide (NO) is an inhibitory neurotransmitter of intestinal smooth muscle cells. The aim of this study was to determine the role of NO in the contractility of rabbit small intestine smooth muscle in vitro. The amplitude, frequency and tone of spontaneous contractions in longitudinal and circular smooth muscle of duodenum, jejunum and ileum were determined and the sodium nitroprusside (SNP), acetylcholine (ACh) and KCl responses were quantified. L-NAME, L-NNA, L-arginine and D-arginine did not affect the amplitude, frequency and tone of spontaneous contractions. ODQ (10-6 M) increased the tone of spontaneous contractions of the types of tissues examined, and the amplitude in ileum, without modifying the frequency. SNP (10-4 M) evoked relaxations that were not influenced by atropine (10-6 M) plus guanethidine (10-6 M), apamin (10-8 M) or glybenclamide (10-6 M), but were increased by TTX (10-6 M) and verapamil (10-7 M). SNP-induced relaxations were reduced by charybdotoxin (10-8 M) and ODQ (10-6 M). ODQ (10-5 M) reduced ACh-induced contractions, but it did not influence KCl-evoked contractions. Those results suggest that NO modulates the spontaneous contractions of small intestine in rabbits. This effect is mediated by cGMP and Ca2+-dependent K+ channels of large conductance.
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