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Interaction of hierarchical nanoporous carbons (HNCs) with chicken embryo red blood cells (RBC)

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Bugajska Z., Jaworski S., Daniluk K., Biniecka P., Sosnowska M.

Annals of Warsaw University of Life Sciences - SGGW. Animal Science

2017

tom 56[1]

Interaction of hierarchical nanoporous carbons(HNCs) with chicken embryo red blood cells (RBC.The purpose of this study was to characterize toxicity of hierarchical nanoporous carbons (HNCs) on chicken embryo red blood cells (RBC). RBC are a perfect model to adapt the hemolysis assay in evaluation of the in vitro blood compatibility of nanoparticles. The samples of blood were treated with different concentration of HNCs (10 µg/ml, 50 µg/ml and 100 µg/ml). Hemolysis assay showed that the hemolytic activity depends on the dose of HNCs. The microscope observations have shown a difference in morphology between treated and untreated RBC: changes in cell membrane shape and the occurrence of pathological erythrocytes forms.

Ograniczanie wyników

1 Annals of Warsaw University of Life Sciences - SGGW. Animal Science

1 Biniecka P.

1 Bugajska Z.

1 Daniluk K.

1 Jaworski S.

1 Sosnowska M.

1 2017

Wyniki wyszukiwania

Interaction of hierarchical nanoporous carbons (HNCs) with chicken embryo red blood cells (RBC)