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N4-amino-acid derivatives of 6-azacytidine: structure - activity relationship

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Alexeeva I., Palchikovskaya L., Shalamay A., Nosach L., Zhovnovataya V., Povnitsa O., Dyachenko N.

Acta Biochimica Polonica

2000

tom 47

nr 1

Several N4-derivatives of 6-azacytidine were synthesized using of Vorbrueggen's condensation method. Their antiviral activity with respect to the adenovirus serotypes 2 and 5 in Hep-2 cells culture was studied and primary specific activity was determined. Correlation between chemical structure of new 6-azacytidine derivatives and their biological properties is discussed.

Ograniczanie wyników

1 Acta Biochimica Polonica

1 Alexeeva I.

1 Dyachenko N.

1 Nosach L.

1 Palchikovskaya L.

1 Povnitsa O.

1 Shalamay A.

1 Zhovnovataya V.

1 2000

Wyniki wyszukiwania

N4-amino-acid derivatives of 6-azacytidine: structure - activity relationship