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Phosphorylation of yeast ribosomal proteins by CKI and CKII in the presence of heparin

100%

Wojda I., Cytrynska M., Frajnt M., Jakubowicz T.

Acta Biochimica Polonica

1999

tom 46

nr 1

We have found that heparin has a different effect on Trichosporon cutaneum ribosomal protein phosphorylation by CKI and by CKII. In the presence of heparin, modification of 13 kDa, 19 kDa and 38 kDa proteins catalyzed by CKII was inhibited, while in the case of CKI, in addition to protein of 15 kDa, phosphorylation of 20 kDa and 35 kDa proteins was detected. It was also found that, in the presence of heparin, phosphorylation of P proteins (13 kDa and 38 kDa) by ribosome-bound protein kinases was inhibited. Moreover at the same conditions modification of 40 kDa protein was observed in all four yeast species tested.

Ograniczanie wyników

1 Acta Biochimica Polonica

1 Cytrynska M.

1 Frajnt M.

1 Jakubowicz T.

1 Wojda I.

1 1999

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Phosphorylation of yeast ribosomal proteins by CKI and CKII in the presence of heparin