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Analysis of genomic instability in primary spermatocytes of interspecific hybrids of the red fox (Vulpes vulpes) and the arctic fox (Alopex lagopus)

100%

Bugno-Poniewierska M., Pawlina K., Jakubczak A., Jezewska-Witkowska G.

Folia Biologica

2014

tom 62

nr 4

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Genome instability in fruit body derived lines generated from fruiting pfle somatic hybrid lines and development of hybrid strain specific SCAR marker in edible mushroom

100%

Mallick P., Sikdar S. R.

Journal of Horticultural Research

2015

tom 23

nr 2

Aneuploidy, chromosomal missegregation, and cell cycle reentry in Alzheimer's disease

80%

Zekanowski C., Wojda U.

Acta Neurobiologiae Experimentalis

2009

tom 69

nr 2

232-253

Alzheimer's disease (AD) is a neurodegenerative disorder with a complex etiology and pathogenesis. Chromosome missegregation was proposed two decades ago to be responsible for neurodegeneration in AD patients. It was speculated that the aneuploidy is a result of aberrant cell cycle of neuronal progenitors during adult neurogenesis and/or of mature neurons. There is mounting evidence of increased rate of general aneuploidy and cell cycle reentry in the AD patients' brains, with area-specific pattern. In this review, we discuss the involvement of chromosome instability, genome damage and cell cycle impairment in AD pathology.

Ograniczanie wyników

1 Acta Neurobiologiae Experimentalis

1 Folia Biologica

1 Journal of Horticultural Research

1 Bugno-Poniewierska M.

1 Jakubczak A.

1 Jezewska-Witkowska G.

1 Mallick P.

1 Pawlina K.

1 Sikdar S. R.

1 Wojda U.

1 Zekanowski C.

1 2015

1 2014

1 2009

Wyniki wyszukiwania

Analysis of genomic instability in primary spermatocytes of interspecific hybrids of the red fox (Vulpes vulpes) and the arctic fox (Alopex lagopus)

Genome instability in fruit body derived lines generated from fruiting pfle somatic hybrid lines and development of hybrid strain specific SCAR marker in edible mushroom

Aneuploidy, chromosomal missegregation, and cell cycle reentry in Alzheimer's disease