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1

Ghrelin gastric tissue expression in patients with morbid obesity and type 2 diabetes submitted to laparoscopic sleeve gastrectomy: immunohistochemical and biochemical study

100%
Mehdar K. M., Alsareii S. A. M., Alshafie S. E. M., Al-Rafiah A. R., Alamri A. M.
Folia Histochemica et Cytobiologica
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2020
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tom 58
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nr 4
2
Content available remote

The role of prednisolone and epinephrine on gastric tissue and erythrocyte antioxidant status in adrenalectomized rats

100%
Yildirim A., Sahin Y. N., Suleyman H., Yilmaz A., Yildirim S.
Journal of Physiology and Pharmacology
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2007
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tom 58
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nr 1
It has been believed that overproduction of free radicals and/or deficiency of antioxidant systems, and stress hormones may play a role in etiopathogenesis of many diseases, including gastric ulcer. This study evaluated whether there was an effect of adrenalectomy on lipid peroxidation [malondialdehyde (MDA)] and antioxidant [superoxide dismutase (SOD), glutathione peroxidase (GPX) and glutathione (GSH) levels] systems in gastric tissue and erythrocyte in rats. As well, the impacts of administration of prednisolone and epinephrine on these systems in adrenalectomized rats were investigated. Thirty-three rats were randomly grouped as sham-operated (group I), adrenalectomized (group II), adrenalectomized + prednisolone (group III) and adrenalectomized + epinephrine (group IV). After experimental procedures, blood and gastric tissues samples were taken from each animal in all groups. Colorimetric assays were employed to determine gastric tissue and erythrocyte levels of MDA and GSH, and SOD and GPX activities. Adrenalectomy in group II rats caused a marked decrease of SOD and GPX activities and MDA levels, and an increase of GSH levels in gastric tissue and erythrocyte, when compared to sham-operated rats. However, especially epinephrine injection after adrenalectomy resulted in a significantly increase of measured antioxidant enzyme activities and GSH levels in both gastric tissue and erythrocyte. These results indicate that adrenalectomy appeared to alter the levels of antioxidants and lipid peroxidation product in gastric tissue and erythrocyte. Thus, the present study provides a physiological regulatory role of adrenal gland in the maintenance of oxidant/antioxidant balance in gastric tissue and erythrocyte.
3
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Expression of serum response factor in normal rat gastric mucosa

100%
Chai J., Baatar D., Moon W., Tarnawski A.
Journal of Physiology and Pharmacology
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2002
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tom 53
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nr 2
Serum response factor (SRF) is a transcription factor that is involved in cell proliferation, muscle and neuron development and maintenance. Its expression in gastric mucosa remains unknown. In this study we demonstrated that SRF is expressed in normal rat gastric tissue as two isoforms and localized mainly to smooth muscle cells of muscularis mucosae and its extensions into the lamina propria, to muscularis propria, and musculature of the vascular system. To a lesser extent, SRF is also expressed in the gastric epithelium of the mucosal neck area (proliferative zone) and in the endothelial cells of microvessels. These data suggest that the main role of SRF in normal gastric tissue is to maintain muscular support and contraction and possibly epithelial regeneration.
4

Consumption of Citrullus colocynthis fruit extract causes histological and immunological alterations in mice

80%
Bahloul R. S., Aljahdali M. O., Redwan E. M.
Folia Biologica
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2020
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tom 68
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nr 4
5
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Content available

Relationship between vascular endothelial growth factor and angiogenesis in spontaneous and indomethacin-delayed healing of acetic acid-induced gastric ulcers in rats

80%
Suzuki N., Takahashi S., Okabe S.
Journal of Physiology and Pharmacology
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1998
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tom 49
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nr 4
6
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Bismuth therapy for Helicobacter pylori infection. A review of five years experience at a University Hospital in Norway

61%
Berstad A., Olafsson S., Tefera S., Berstad K., Hundal O., Bergseth M., Wilhelmsen I.
Journal of Physiology and Pharmacology
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1996
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tom 47
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nr 1
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