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Protection of cattle against bovine leukemia virus [BLV] infection could be attained by DNA vaccination

100%

Brillowska A., Dabrowski S., Rulka J., Kubis P., Buzala E., Kur J.

Acta Biochimica Polonica

1999

tom 46

nr 4

The bovine leukemia virus (BLV) envelope gene encoding extracellular glycoprotein gp51 and transmembrane glycoprotein gp30 was cloned into a vehicle expression vector under the human cytomegalovirus (CMV) intermediate early promoter. The intramuscular injection of this plasmid vector generated a cellular immune response. Seven out of ten cows vaccinated with the DNA construct resisted a drastic challenge (500 BLV-infected lymphocytes as an infectious dose).

Ograniczanie wyników

1 Acta Biochimica Polonica

1 Brillowska A.

1 Buzala E.

1 Dabrowski S.

1 Kubis P.

1 Kur J.

1 Rulka J.

1 1999

Wyniki wyszukiwania

Protection of cattle against bovine leukemia virus [BLV] infection could be attained by DNA vaccination