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Activity of catabolic enzymes of film-forming strains of Staphylococcus aureus

100%
Voronkova O. S., Shevchenko T. M., Vinnikov A. I.
International Letters of Natural Sciences
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2017
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tom 61
The activity of glucose catabolism pathways of film-forming strains of staphylococci isolated from vagina of women with dysbiosis of reproductive tract and from women without disorders of microflora was studied. It was established that the investigated film-forming strains utilized the carbohydrates by pentose phosphate pathway mainly, as indicated by 23-33% higher enzyme activity compare to strains isolated from healthy women. Instead strains, isolated from women without dysbiosis of reproductive tract, have higher activity of glycolytic enzymes on 13- 28%. The prevalence of glycolytic transformation of glucose by strains isolated from healthy women also indicates by the depression of glucose oxidation during action of monoiodinacetate – classical inhibitor of glycolysis. It inhibits glycolysis of strains isolated from healthy women more significant. It was established that oxidase activity of film-forming strains isolated from women with dysbiosis, increased over 40% during the use of basic substrates of citric acid cycle. These data indicate a general increase of catabolic activity of oxidative type of staphylococci isolated during vaginal dysbiosis and able to form biofilm.
2
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Hazards to humans and animals associated with antibiotic misuse

67%
Micinski J., Pogorzelska J., Slyamowa A., Kobzhassarov T., Bermagambetova N., Dzik S., Kowalski P. M., Zaborowska-Sapeta K., Kowalski I. M.
Journal of Elementology
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2015
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tom 20
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nr 4
The increasing resistance of community and hospital acquired bacterial strains has become a challenge to the current health policy in Poland. Although some bacteria are known to have a peculiar resistance towards a given agent, antibiotics have a well-established position in clinical practice and are broadly available in our lives. The universal access to antimicrobial therapy and its overuse have created an issue of previously susceptible bacteria now presenting antibiotic resistance. All bacteria that survive antibiotic treatment, continue growth and reproduction. This phenomenon is also observed in livestock rearing. An inadequate implementation of antibiotic therapy leads to the transfer of resistant bacterial strains into the environment of people, who eat products of animal and plant origin. Moreover, the non-compliance to law in terms of antibiotics added to animal fodder or negilgence of withdrawal periods seems to further exacerbate the situation. Various research projects conducted in Poland and elsewhere have demonstrated that antibiotics produce an immunosuppressive effect, which exposes both humans and animals to different infections. Antibiotics also interfere with the growth of many microorganisms, recognized as part of the human and animal physiological microflora, as a result of which dysbacteriosis may develop. In order to limit the use of antibiotics in animal husbandry, research should be focus on finding alternative agents based on plant extracts that undergo biodegradation.
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Najczęstsze przyczyny i objawy niepożądanych reakcji pokarmowych u pacjentów weterynaryjnych

34%
Stilwell N.
Weterynaria po Dyplomie
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2019
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tom 20
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nr 5
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