Basal Stem Rot (BSR) disease caused by Ganoderma lucidum (Leys) Karst, is the most destructive disease and a major constraint in coconut production. Fifty five endophytic strains of bacteria were isolated from coconut roots of different regions. Among the isolates, EPC5 (Endophytes coconut), EPC8, EPC15, EPC29, EPC52 and Pfl (Plant growth promoting rhizobacteria) promoted the rice seedling growth in roll towel and pot culture method. EPC5 (Plant growth promoting endophytic bacteria), Pf1 and Trichoderma viride (Plant growth promoting fungus) effectively inhibited the G. lucidum growth in vitro. When bioagents along with farm yard manure (FYM) were heaped for different days interval the population was increased in twenty days both in sterilized and unsterilized conditions.