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Measurement of functional independence level and falls-risk in individuals with ungiagnosed phenylketonuria

100%

Mazur A., Jarochowicz S., Oltarzewski M., Sykut-Cegielska J., Kwolek A., O'Malley G.

Acta Biochimica Polonica

2009

tom 56

nr 4

613-618

The aim of the study was to determine the level of functional independence in adult patients with previously undiagnosed or untreated phenylketonuria (PKU). The study was conducted among 400 intellectually impaired adult residents of Social Welfare Homes in South-Eastern Poland born prior to the introduction of neonatal PKU screening programs. PKU was screened by filter paper test using tandem mass spectrometry methods, and confirmed by gas chromatography-mass spectrometric analysis of PKU organic acids in urine. Degree of functional independence included the assessment of activities of daily living (Barthel Index) and measures of balance and gait (Tinetti scale). Eleven individuals with previously untreated PKU were identified whereby eight presented with moderate disability and three with mild disability. Six had a high risk of falls and five had a moderate risk of falls. This study indicates that there is considerable number of undiagnosed PKU patients within the Polish population who require assessment and management in order to reduce the impact of the neurological and neuropsychiatric problems associated with the condition. Appropriate therapy for those with undiagnosed PKU should, in particular, address the risk of falls.

Cyclical nocturnal oxygen desaturation and impact on activities of daily living in elderly patients

100%

Frohnhofen H., Heuer H. C., Pfundner N., Orth G.

Journal of Physiology and Pharmacology. Supplement

2007

tom 58

nr 5

Influence of type of treatment for sleep apnea on activities of daily living in a sample of elderly patients with severe sleep apnea

80%

Frohnhofen H., Heuer H. C., Kanzia A., Firat A.

Journal of Physiology and Pharmacology. Supplement

2009

tom 60

nr 5

Ograniczanie wyników

2 Journal of Physiology and Pharmacology. Supplement

1 Acta Biochimica Polonica

2 Frohnhofen H.

2 Heuer H. C.

1 Firat A.

1 Jarochowicz S.

1 Kanzia A.

1 Kwolek A.

1 Mazur A.

1 O'Malley G.

1 Oltarzewski M.

1 Orth G.

1 Pfundner N.

1 Sykut-Cegielska J.

2 2009

1 2007

Wyniki wyszukiwania

Measurement of functional independence level and falls-risk in individuals with ungiagnosed phenylketonuria

Cyclical nocturnal oxygen desaturation and impact on activities of daily living in elderly patients

Influence of type of treatment for sleep apnea on activities of daily living in a sample of elderly patients with severe sleep apnea