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Dactinomycin-induced veno-occlusive disease in rats. The hepatoprotective action of amifostine. Evaluation in a light and electron microscope

100%

Borowska H., Arciszewska E., Czauderna P., Sawicki B.

Folia Morphologica

2004

tom 63

nr 1

The purpose of the study was to draw upan experimental model of hepatic veno-occlusive disease (VOD) induced by dactinomycin (ACT) and to investigate the possible hepatoprotective effects of Ethyol (amifostine). Pathological changes corresponding to a VOD picture of varying intensification were found in the liver samples obtained from all the rats receiving ACT. Amifostine appears to act protectively to liver changes caused by dactinomycin.

Ograniczanie wyników

1 Folia Morphologica

1 Arciszewska E.

1 Borowska H.

1 Czauderna P.

1 Sawicki B.

1 2004

Wyniki wyszukiwania

Dactinomycin-induced veno-occlusive disease in rats. The hepatoprotective action of amifostine. Evaluation in a light and electron microscope