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1

Toxic effects of pesticides on cholinesterase and hepatic functions in exposed workers

100%
Milosevic M., Popara D., Antic R., Jankovljevic B., Plecas D.
Annals of Agricultural and Environmental Medicine
|
1994
|
tom 01
|
nr 2
2

The activity of cholinesterases in diapausing and flying red mason bees Osmia bicornis (Megachilidae)

86%
Dmochowska-Slezak K., Zaobidna E., Domeracka J., Swiatkowska M., Rusznica M., Zoltowska K.
Folia Biologica
|
2015
|
tom 63
|
nr 4
3

Non-specific esterase polymorphism in marginal populations of Cyprinotus (Heterocypris) barbarus (Gauthier et Brehm) (Crustacea, Ostracoda)

86%
Sywula T., Sell J., Wozniak G., Sobolewska A.
Bulletin of the Polish Academy of Sciences. Biological Sciences
|
1991
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tom 39
|
nr 4
4

Interaction of lindane and carbaryl with cholinesterase activity in rats

86%
Krechniak J., Englot B.
Acta Poloniae Toxicologica
|
1994
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tom 02
|
nr 1
5

The morphology and histochemistry of adult rats neurocytes after BCNU administration

72%
Godlewski A., Szczech J.
Folia Histochemica et Cytobiologica
|
1985
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tom 23
|
nr 4
6

Cholinergic components of the nervous system of the digenean parasites, Haplorchoides cahirinus and Acanthostomum absconditum from the catfish Bagrus bayad in Egypt

72%
Arafa S. Z., Reda E. S., El-Naggar M. M.
Acta Parasitologica
|
2002
|
tom 47
|
nr 4
A comparison has been made for the first time between the cholinergic components of the nervous system of the intestinal digeneans, Acanthostomum absconditum and Haplorchoides cahirinus from catfish, Bagrus bayad caught in Egypt. Some important differences in the central and the peripheral nervous systems are recorded between the two digeneans. The number of transverse connectives in A. absconditum is greater than in H. cahirinus, while the number of ring commissures in H. cahirinus (10) is greater in A. absconditum (3). Innervation of the subtegumental muscles, anal opening, excretory pores and ootype are revealed only in A. absconditum. Many cholinergic bipolar and multipolar nerve cell bodies (somata) are evident in A. absconditum. These cells lie close to the dorsal surface and are associated with the dorsal nerve cords and nerves supplying the subtegumental muscles. Possible functions of some nervous components are discussed.
7

Screening for cholinesterase inhibitors in selected fruits and vegetables

58%
Szwajgier D., Borowiec K.
Electronic Journal of Polish Agricultural Universities. Series: Biotechnology
|
2012
|
tom 15
|
nr 2
8
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Effects of stress pretreatment on the dynamics of blood cholinesterase activity after exposure to an organophosphorus pesticide in the rat

58%
Gralewicz S., Swiercz R., Lutz P., Wiaderna D., Wasowicz W.
Annals of Agricultural and Environmental Medicine
|
2010
|
tom 17
|
nr 1
65-71
9

Effects of niclosamide on Oncomelania hupensis, the intermediate snail host of Schistosoma japonicum: an enzyme-histochemical study

58%
Wang W., Li H., Liang Y., Dai J.
Acta Parasitologica
|
2009
|
tom 54
|
nr 2
172-179
An enzyme-histochemical study of five enzymes, namely succinate dehydrogenase (SDH), lactate dehydrogenase (LDH), cytochrome oxidase (CCO), cholinesterase (CHE) and nitric oxide synthase (NOS), was elucidated in the soft tissues of Oncomelania hupensis, the intermediate host snail of Schistosoma japonicum, before and after the treatment with a suspension concentrate of niclosamide (SCN). Following the treatment of SCN, a marked loss occurred in the activity of the five enzymes mentioned above. LDH and SDH showed their strongest activity in the buccal mass and muscular fibers, CCO in buccal mass and liver, CHE in pellicle and ganglia, and NOS in muscular fibers and pharyngeal canal. The results indicate that SCN impairs the activities of the enzymes influencing the transfer of neurotransmitter and energy supply in O. hupensis, ultimately leading to the loss of various physiological functions, which is considered to be a cause of death in O. hupensis.
10

Effect of alpha-cypermethrin and chlorpyrifos in a 28-day study on free radical parameters and cholinesterase activity in Wistar rats

58%
Wielgomas B., Krechniak J.
Polish Journal of Environmental Studies
|
2007
|
tom 16
|
nr 1
In the current study the influence of single compounds and concurrent exposure to popular insecticides: organophosphate (OP) – chlorpyrifos (CPF) and synthetic pyrethroid (PYR ) – α-cypermethrin (CM) on some oxidative stress parameters and cholinesterase (ChE) activity in rats was investigated. Animals received by gavage 10 mg of single compounds or 5 mg of each per kg bw daily in rapeseed oil for 14 and 28 days. Concentrations of total thiols and TBARS, activity of catalase and cholinesterase were measured in tissues. Total thiol concentrations declined in plasma in all experimental groups after 14 and 28 days, while in liver a decrease was noted after only 14 days in animals receiving CPF and after 28 days in rats treated with CM alone with a mixture of pesticides. Lipid peroxidation presented as TBARS concentration was elevated mostly after 2 weeks of exposure in brain and liver but not in plasma in all experimental groups. Catalase activity increased in erythrocytes in all groups treated with insecticides, while in liver CM administered alone reduced the activity of the enzyme. Cholinesterase was markedly depressed to a different degree in plasma and brain of animals receiving CPF alone or in combination, while CM did not significantly elevate brain ChE. The results of this study seem to indicate that CM and CPF apart from known modes of action demonstrate their toxicity also through free radical mediated mechanisms. It is also evident that CM administered with CPF does not affect the cholinesterase inhibition generated by the latter.
11

Tenocyclidine treatment in soman-poisoned rats - intriguing results on genotoxicity versus protection

58%
Petek M. J., Berend S., Kopjar N., Zeljezic D., Mladinic M., Radic B., Vrdoljak A. L.
Acta Biochimica Polonica
|
2008
|
tom 55
|
nr 1
This study aimed to evaluate the antidotal potency of tenocyclidine (TCP) that probably might protect acetylcholinesterase (AChE) in the case of organophosphate poisoning. TCP was tested alone as a pretreatment or in combination with atropine as a therapy in rats poisoned with ¼ and ½ of LD50 of soman. Possible genotoxic effects of TCP in white blood cells and brain tissue were also studied. Results were compared with previous findings on the adamantyl tenocyclidine derivative TAMORF. TCP given alone as pretreatment, 5 min before soman, seems to be superior in the protection of cholinesterase (ChE) catalytic activity in the plasma than in brain, especially after administration of the lower dose of soman. Plasma activities of the enzyme after a joint treatment with TCP and soman were significantly increased at 30 min (P < 0.001) and 24 h (P = 0.0043), as compared to soman alone. TCP and atropine, given as therapy, were more effective than TCP administered alone as a pretreatment. The above therapy significantly increased activities of the enzyme at 30 min (P = 0.046) and 24 h (P < 0.001), as compared to controls treated with ¼ LD50 of soman alone. Using the alkaline comet assay, acceptable genotoxicity of TCP was observed. However, the controversial role of TCP in brain protection of soman-poisoned rats should be studied further.
12

Histochemical and enzyme-histochemical studies of Oncomelania hupensis (Gredler, 1881), the intermediate host of Schistosoma japonicum

51%
Wang W., Dai J., Li H., Liang Y.
Acta Parasitologica
|
2011
|
tom 56
|
nr 1
The distribution of glycogen, DNA and histone, and localization of activity of ten enzymes such as glucose-6-phosphatase (G-6-Pase), cytochrome oxidase (CCO), lactate dehydrogenase (LDH), 5′-nucleotidase (5′-NT), succinate dehydrogenase (SDH), glucose-6-phosphate dehydrogenase (G-6-PDH), alkaline phosphatase (ALP), acid phosphatase (ACP), Mg2+-adenosine triphosphatase (Mg2+-ATPase), and cholinesterase (CHE) in Oncomelania hupensis (Gredler, 1881) snails, the intermediate host of Schistosoma japonicum, was surveyed using the histochemical and enzyme-histochemical techniques. The results showed that the glycogen with high activity was widely distributed in snails. DNA showed its strongest reaction in testis. The histone was distributed in sites of the radula, parenchyma of penis and ovary. LDH and SDH were widely distributed in snails and all were abundant. Sites of the strongest enzyme activities of G-6-PDH were evident in the reproductive system together with central ganglia. Only the ovary showed a strong enzyme activity of G-6-Pase. Most tissues and organs contained CCO, and the activity of this enzyme was very strong. 5′-NT showed a strong enzyme activity in the ovary and testis. Mg2+-ATPase was localized in sites of the liver, stomach and reproductive gland. A strong enzyme activity of ALP appeared in the digestive system. ACP showed a low activity in snails. The central ganglia, nervous stem, liver, branchial duct, epithelia of the head and foot regions showed a very strong enzyme activity of CHE. The findings could provide a theoretical basis for development of highly effective molluscicides with low toxicity to other biota, as well as means for novel snail control strategies.
13

Badania zaburzeń metabolicznych u krów produkcyjnych z wybranych gospodarstw na Żuławach. I. Wskaźniki hematologiczne i przemiany białkowej

30%
Kuleta Z., Depta A., Pomianowski A., Bronicki M., Polakowska-Nowak G., Wosek J.
Acta Academiae Agriculturae ac Technicae Olstenensis. Veterinaria
|
1990
|
tom 19
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