Wyniki wyszukiwania

1

Patterns of intrathoracic gas volume and airway resistance in children with asthma

100%

Kalhoff H., Lara E., Kiwull P., Kiwull-Schone H.

Journal of Physiology and Pharmacology. Supplement

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2007

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tom 58

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nr 5

2

Skeletal muscle relaxants inhibit rat tracheal smooth muscle tone in vitro

100%

Milchert M., Spassov A., Meissner K., Nedeljkov V., Lehmann C., Wendt M., Loster B. W., Mazurkiewicz-Janik M., Gedrange T., Pavlovic D.

Journal of Physiology and Pharmacology. Supplement

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2009

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tom 60

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nr 8

5-11

3

Glutathione prevents the early asthmatic reaction and airway hyperresponsiveness in guinea pigs

100%

Kloek J., Mortaz E., Van Ark I., Lilly C. M., Nijkamp F. P., Folkerts G.

Journal of Physiology and Pharmacology

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2010

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tom 61

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nr 1

67-72

The prevalence of asthma has increased worldwide. The reasons for this rise remain unclear. Oxidative stress plays an important role in the pathogenesis of asthma. Glutathione (GSH) is the major representative of the class of nonprotein thiols and plays a pivotal role in a variety of enzymatic and nonenzymatic reactions that protect tissues against oxidative stress. In antioxidative reactions, GSH is converted into its oxidized form, glutathione disulfide (GSSG) that in its turn is enzymatically reduced into GSH to maintain a physiological redox balance. We used a guinea pig model of asthma to assess whether the early asthmatic reaction is associated with decreased lung levels of glutathione, and whether decreased glutathione is implicated in the increased airway smooth muscle reactivity that is associated with exposure of the lungs to allergen. Lung glutathione levels were decreased immediately after the onset of the early asthmatic reaction in vivo and associated with the release of 8-iso-PGF2alpha, an indicator for oxidative stress. Glutathione ethylester, a glutathione precursor, blunted the airway obstruction during an early asthmatic reaction in a perfusion model and glutathione depletion rendered the airways hyperreactive. Glutathione ethyl ester in the buffer prevented this hyperreactivity. These results indicate that glutathione can modulate the early asthmatic reaction as well as the airway hyperresponsiveness.

4

Plasminogen activator inhibitor-1 [PAI-1] and urokinase plasminogen activator [uPA] in sputum of allergic asthma patients

100%

Kowal K., Zukowski S., Moniuszko M., Bodzenta-Lukaszyk A.

Folia Histochemica et Cytobiologica

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2008

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tom 46

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nr 2

193-198

5

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Swine confinement buildings: effects of airborne particles and settled dust on airway smooth muscles

100%

Demanche A., Bonlokke J. H., Beaulieu M.-J., Assayag E. I., Cormier Y.

Annals of Agricultural and Environmental Medicine

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2009

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tom 16

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nr 2

233-238

6

GM-CSF regulation in eosinophils

100%

Esnault S., Malter J. S.

Archivum Immunologiae et Therapiae Experimentalis

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2002

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tom 50

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nr 2

7

Teophylline inhibits free oxygen radicals production by human monocytes via phosphodiesterase inhibition

80%

Chorostowska-Wynimko J., Kus J., Skopinska-Rozewska E.

Journal of Physiology and Pharmacology. Supplement

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2007

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tom 58

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nr 5

8

Cytoplasm-nuclear trafficking of CREB and CREB phosphorylation at Ser133 during therapy of chronic obstructive pulmonary disease

80%

Mroz R. M., Holownia A., Chyczewska E., Drost E. M., Braszko J. J., Noparlik J., Donaldson K., Macnee W.

Journal of Physiology and Pharmacology. Supplement

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2007

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tom 58

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nr 5

9

Biphasic response to lipopolysaccharide from E.coli in the isolated ventilated blood-perfused rat lung

80%

Chlopicki S., Bartus J. B., Gryglewski R. J.

Journal of Physiology and Pharmacology

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1999

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tom 50

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nr 4

Ograniczanie wyników

Patterns of intrathoracic gas volume and airway resistance in children with asthma

Skeletal muscle relaxants inhibit rat tracheal smooth muscle tone in vitro

Glutathione prevents the early asthmatic reaction and airway hyperresponsiveness in guinea pigs

Plasminogen activator inhibitor-1 [PAI-1] and urokinase plasminogen activator [uPA] in sputum of allergic asthma patients

Swine confinement buildings: effects of airborne particles and settled dust on airway smooth muscles

GM-CSF regulation in eosinophils

Teophylline inhibits free oxygen radicals production by human monocytes via phosphodiesterase inhibition

Cytoplasm-nuclear trafficking of CREB and CREB phosphorylation at Ser133 during therapy of chronic obstructive pulmonary disease

Biphasic response to lipopolysaccharide from E.coli in the isolated ventilated blood-perfused rat lung