Osteocalcin is synthesized by osteoblasts and incorporated into bone matrix. During bone resorption by osteoclasts, osteocalcin is released from bone matrix. Plasma osteocalcin level may be used as a bone turnover marker. The aim of the study was to assess a relationship between osteocalcin level in blood and forearm bone mineral density in women. Significant negative correlation between osteocalcin concentration and bone mineral density of forearm mid distal region was found.