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Analysis of a fusion between rat glioma cells and biomimetic liposomes with encapsulated diamond nanoparticles or curcumin

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Strojny B., Grodzik M., Sawosz E., Gromadka M.

Annals of Warsaw University of Life Sciences - SGGW. Animal Science

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2016

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tom 55[2]

Analysis of a fusion between rat glioma cells and biomimetic liposomes with encapsulated diamond nanoparticles or curcumin. Liposomes are used as carriers for different bioactive agents, both hydrophilic, which are encapsulated in water core of the liposome, and hydrophobic, which are entrapped within liposome walls. The walls are built from phospholipid bilayer, therefore their structure resembles cell membrane. It was hypothesized that if the wall is made of set of lipids typical for a cell, the liposome will be eagerly consumed by the cell. We performed the experiments using C6 rat glioma cells as an example, since central nervous system cells are extremely rich in lipids, including the unique ones. Since all cancer cells have high proliferation potential, they need to absorb precursors to build cell membrane around new cells, therefore such biomimetic liposomes may be one of the most effective way to deliver anticancer agents into the cell. Analysis of physicochemical properties of obtained liposomes, as well as in vitro tests, showed that obtaining such liposomes is possible and that the liposomes are biocompatible, stable carrier both for hydrophilic and hydrophobic agents. Encapsulation of diamond nanoparticles did not affect the liposomes, whereas entrapping of curcumin, which is a spice known in traditional Asian medicine for its anticancer properties, significantly increased its activity. Obtained results showed that biomimetic liposomes can be effective, individually-tailored carriers for bioactive agents.

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Observations of plants with tubular stems with possible biomimetic implications

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Goto M., Wang A., Goto H.

International Letters of Natural Sciences

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2015

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tom 43

Two plants having tubular stems were examined. Water lily belongs to nymphaeaceae, while butterbur belongs to asteraceae. These plants are not relatives; however both have large leaves with lacinia. Furthermore, these plants have tubular long stems. Observations of leaf surface are described. Water lily leaf has an inside layer consisting of a network polygonal structure. The leaf has three layers at the microscopic level including small transparent skin tissue, and a middle layer showing a polygonal green structure where photosynthesis can be performed. The bottom layer shows fine tubular tissues. Stomas are observed on the surface of the leaf, with transparent tissue on the top layer and the stem of the butterbur with honeycomb (polygonal) structures in the leaves and stems. Plants are of interest for technology because their remarkable functional structure may provide clues for applications in materials science. In this study, the fine structures of the two plants were observed to learn their functional structure.

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To sustainability through interdisciplinary planning: a planner's perspective

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Kozlowski J.

Problemy Rozwoju Miast

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2008

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tom 05

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nr 1

There are many terms describing planning for towns and settlements. The term 'Town and Regional Planning' has been commonly used in the British Commonwealth countries while ‘Urban Planning’ and Land Use Planning’ has been more popular in the USA. Frequently used terms are also: 'Physical Planning'; 'Town and Country Planning' ;'Spatial Planning' and 'Settlement Planning', a favoured UN term. In Queensland, Australia, the recent Integrated Planning Act 1997 applied a term of 'Planning'. The term ‘Environmental Planning’, also well known, was defined by the International Union for Conservation of Nature as: "...a process whereby regional, national or subnational resource conservation or development plans are created in ways that consciously seek to minimise long term negative effects on existing levels of environmental quality ..." There are, however, views which consider Environmental Planning as all planning, that is, including planning for regions, towns and settlements of various kind (see, for instance, Faludi, 1987, Evans, 1997 or the actual New South Wales planning legislation). For this paper, originated in Queensland, the use of the term ‘planning’ was thought the appropriate choice.

Ograniczanie wyników

1 Annals of Warsaw University of Life Sciences - SGGW. Animal Science

1 International Letters of Natural Sciences

1 Problemy Rozwoju Miast

1 Goto H.

1 Goto M.

1 Grodzik M.

1 Gromadka M.

1 Kozlowski J.

1 Sawosz E.

1 Strojny B.

1 Wang A.

1 2016

1 2015

1 2008

Analysis of a fusion between rat glioma cells and biomimetic liposomes with encapsulated diamond nanoparticles or curcumin

Observations of plants with tubular stems with possible biomimetic implications

To sustainability through interdisciplinary planning: a planner's perspective