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  1. 10 Journal of Physiology and Pharmacology

  2. 4 Journal of Physiology and Pharmacology. Supplement

  3. 3 BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

  4. 3 Herba Polonica

  5. 2 Folia Histochemica et Cytobiologica

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  1. 3 Yuksel M.

  2. 2 Kasimay Cakir O.

  3. 1 A S.-X.

  4. 1 Abd El-Hamid S. R.

  5. 1 Abo Raya D. S. A.

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  1. 2 2021

  2. 1 2020

  3. 2 2019

  4. 2 2018

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1
Content available remote

The essential oil from Ferulago angulata (Schltdl.) Boiss. fruits exerting potent analgesic and anti-inflammatory effects

100%
Shafaroodi H., Roozbahani S., Asgarpanah J.
Journal of Physiology and Pharmacology
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2021
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tom 72
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nr 1
2
Content available remote

Nesfatin-1 protects from acute pancreatitis: role of melanocortin receptors

100%
Buzcu H., Ozbeyli D., Yuksel M., Cilingier Kaya O. T., Kasimay Cakir O.
Journal of Physiology and Pharmacology
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2019
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tom 70
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nr 6
3

Gamma linolenic acid suppresses hypoxia-induced gastric cancer cell growth and epithelial-mesenchymal transition by inhibiting the Wnt/b-catenin signaling pathway

84%
Wang Y., Shi J., Gong L.
Folia Histochemica et Cytobiologica
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2020
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tom 58
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nr 2
4
Content available remote

Relation of adrenergic receptors, which have roles in gastroprotective and anti-inflammatory effect of adrenal gland hormones, with cyclooxygenase enzyme levels in rats

84%
Suleyman H., Dursun H., Bilici M., Cadirci E., Halici Z., Gulaboglu M., Albayrak F.
Journal of Physiology and Pharmacology
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2009
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tom 60
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nr 4
129-134
Background and Aims: COX-2 enzyme inhibition is responsible for the anti-inflammatory effects of NSAIDs, COX-1 for their effects upon the gastrointestinal system (GIS), along with other side effects. We investigated the relationship between COX levels and those adrenergic receptors known to play a role in gastroprotection and anti-inflammatory activity. Method: The effects of adrenaline and prednisolone on gastric COX-1 and COX-2 levels in both intact and adrenalectomized rats treated with doxazosin, yohimbine, propranolol, and metoprolol were determined. Results: We found that adrenaline increases COX-1 levels in the gastric tissue of both intact and adrenalectomized rats by stimulating -2 receptors. Adrenaline decreases COX-2 levels by stimulating ß-2 adrenergic receptors. Prednisolone inhibits both COX-1 and COX-2 in the gastric tissue of intact rats. In adrenalectomized rats, prednisolone increases gastric COX-1 by stimulating -2 receptors, and decreases COX-2 levels by stimulating ß-2 receptors. Conclusion: Prednisolone cannot bind to a adrenergic receptors in the presence of adrenaline (intact rats) but, in its absence (adrenalectomy), binds to -2 receptors, and stimulates them more effectively than adrenaline, suggesting a direct relationship between -2 adrenergic receptors and COX-1 levels, whereas ß-2 receptors are directly related to COX-2 levels.
5
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Content available

Anti-inflammatory effects of medicinal plants mixture used by Bedouin people in Saudi Arabia

84%
Elsharkawy E., Elshathely M., Jaleel G. A., Al-Johar H. I.
Herba Polonica
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2013
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tom 59
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nr 3
Due to toxic and adverse side effects of synthetic drugs, traditional herbal medicine has the potential as a source of new bioactive molecules. That is why we investigated this research, searching new anti-inflammatory drugs from plants growing around us. The anti-inflammatory effect of the mixture of different plants used in traditional medicine (Alkanna tinctoria, Rubia tinctorum and Artemisia herba alba) were studied using carrageenan-induced paw edema (oil mixture extract 100 mg/kg and 200 mg/kg). These material reduces carrageenan-induced inflammation in rats and shows inhibition after 4 h especially at a concentration 200 mg/
6

Anti-inflammatory effects of flavonoids evaluated in murine models: a descriptive review

84%
Carmona-Hernandez J. C., Angel-Isaza J., Gonzalez-Correa C. H., Narvaez-Solarte W.
Animal Science Papers and Reports
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2017
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tom 35
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nr 4
Several chronic diseases are directly related to inflammatory states and lead to tissue damage and failure. Millions of people die worldwide from inflammation-associated pathologies such as cardiovascular diseases, diabetes and obesity. Inadequate dietary habits contribute to a deterioration of these diseases. Diet anti-inflammatory models should be studied in more detail. Fruit and vegetable polyphenols have shown anti-inflammatory benefits. This article is aimed at evaluating the inflammatory response in different murine models administered polyphenol rich diets, with a primary focus on flavonoids extracted from plants and evaluated in several inflammatory induced conditions. Carrageenan as an inflammatory agent was used to induce inflammation and several anti-inflammatory polyphenols were monitored.
7

A novel approach for preventing esophageal stricture formation: olmesartan prevented apoptosis

84%
Dereli M., Krazinski B. E., Ayvaz S., Aksu B., Kanter M., Uzun H., Gelisgen R., Umit C. H., Inan M., Basaran U. N., Pul M.
Folia Histochemica et Cytobiologica
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2014
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tom 52
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nr 1
8

Baicalin attenuates joint pain and muscle dysfunction by inhibiting muscular oxidative stress in an experimental osteoarthritis rat model

84%
Chen D.-S., Cao J.-G., Zhu B., Wang Z.-L., Wang T.-F., Tang J.-J.
Archivum Immunologiae et Therapiae Experimentalis
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2018
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tom 66
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nr 6
9
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Callus cultures of Harpagophytum procumbens (Burch.) DC. ex Meisn. – production of secondary metabolites and antioxidant activity

84%
Grabkowska R., Matkowski A., Grzegorczyk-Karolak I., Wysokinska H.
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
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2015
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tom 96
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nr 1
10
Content available remote

Anti-inflammatory effects of atorvastatin treatment in chronic obstructive pulmonary disease. A controlled pilot study

84%
Mroz R. M., Lisowski P., Tycinska A., Bierla J., Trzeciak P. Z., Minarowski L., Milewski R., Lisowska A., Boros P., Sobkowiak B., Duszewska A. M., Chyczewska E., Musial W. J., Macnee W.
Journal of Physiology and Pharmacology
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2015
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tom 66
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nr 1
11
Content available remote

Anti-inflammatory effects of nesfatin-1 in rats with acetic acid - induced colitis and underlying mechanisms

84%
Ozturk C. C., Oktay S., Yuksel M., Akakin D., Yarat A., Kasimay Cakir O.
Journal of Physiology and Pharmacology
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2015
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tom 66
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nr 5
12

Echinacea purpurea extract (cichoric acid) exerts an anti-inflammatory effect on yak PBMCs and regulates the TLR4 signalling pathway

84%
Xue C.-H., A S.-X., Wang M.-J., Wu Q., Liu J.-H., Zhang L.-F., Wu Y., Wu H., Chai S.-T.
Journal of Veterinary Research
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2021
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tom 65
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nr 1
13
Content available remote

Possible role of garlic oil in ameliorating renal injury after liver ischemia/reperfusion in rats

84%
Lasheen N. N., Elayat W. M., Elrefai M. F. M., Zaki W. S., Ahmed E. H., El Sheikh R. M. N., Abo Raya D. S. A., Gad F. R. S.
Journal of Physiology and Pharmacology
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2019
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tom 70
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nr 5
14

Inhibitory effect of resveratrol on free radical generation in blood platelets

84%
Olas B., Zbikowska H. M., Wachowicz B., Krajewski T., Buczynski A., Magnuszewska A.
Acta Biochimica Polonica
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1999
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tom 46
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nr 4
Resveratrol (3,4',5-trihydroxystilbene), a compound found in many plants, has been shown to prevent coronary heart diseases and to exert a variety of antiinflammatory and anticancerogenic effects. It is effective in lowering the level of serum lipids and in inhibiting platelet aggregation. We evaluated the effect of trans-resveratrol on the production of free radicals in pig blood platelets and showed that resveratrol inhibited the production of different reactive oxygen species (O·2H2O2, singlet oxygen and organic radicals) measured by the luminol-dependent chemiluminescence in resting platelets (P < 0.05). Resveratrol inhibited also the generation of radicals in platelets activated by thrombin (P < 0.05). Treatment of platelets with resveratrol at concentrations of 6.25 and 12.5 μg/ml caused a statistically insignificant increase in the production of O·->2 in these cells, as measured by reduction of cytochrome c; however, at higher doses (25, 50 and 100μg/ml) resveratrol distinctly reduced the generation of O·->2 in platelets (P < 0.05). We suggest that free radicals play an important role in the reduced reactivity of blood platelets induced by resveratrol.
15
Content available remote

Anti-inflammatory effects of nesfatin-1 on acetic acid-induced gastric ulcer in rats: involvement of cyclo-oxygenase pathway

67%
Kolgazi M., Ozdemir-Kumral Z. N., Cantali-Ozturk C., Demirci E. K., Yuksel M., Sirvanci S., Yegen B. C.
Journal of Physiology and Pharmacology
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2017
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tom 68
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nr 5
16
Content available remote

Anticoagulative effects of the inhaled low molecular weight heparin certoparin in healthy subjects

67%
Scheuch G., Brand P., Meyer T., Herpich C., Mullinger B., Brom J., Weidinger G., Kohlhaufl M., Haussinger K., Spannagl M., Schramm W., Siekmeier R.
Journal of Physiology and Pharmacology. Supplement
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2007
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tom 58
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nr 5
17
Content available remote

Antiinflammatory effect of BPC 157 on experimental periodontitis in rats

67%
Keremi B., Lohinai Z., Komora P., Duhaj S., Borsi K., Jobbagy-Ovari G., Kallo K., Szekely A. D., Fazekas A., Dobo-Nagy C., Sikiric P., Varga G.
Journal of Physiology and Pharmacology. Supplement
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2009
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tom 60
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nr 7
18
Content available remote

The role of IL-6 in mediating the anti-inflammatory effects of exercise

67%
Petersen A. M. W., Pedersen B. K.
Journal of Physiology and Pharmacology. Supplement
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2006
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tom 57
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nr 10
43-51
Regular exercise offers protection against all cause mortality and there is evidence from randomised intervention studies that physical training is effective as a treatment in patients with chronic heart diseases, type 2 diabetes and symptoms related to the metabolic syndrome. Chronic diseases such as cardiovascular disease, type 2 diabetes and cancer are associated with chronic low-grade systemic inflammation. It has been demonstrated that regular exercise induces anti-inflammatory effects with elevated levels of anti-inflammatory cytokines and suppression of TNF-alpha production. Thereby, exercise offers protection against TNF-alpha-induced insulin resistance. Otherwise, the exercise-induced production and release of IL-6 from myofibers may contribute to abrogate an atherogenic lipid profile, which is often associated with chronic diseases. This review focuses on the anti-inflammatory effects of exercise and how this may contribute to mediate the beneficial health effects of exercise training in patients with chronic diseases associated with chronic low-grade inflammation.
19
Content available remote

Teophylline inhibits free oxygen radicals production by human monocytes via phosphodiesterase inhibition

67%
Chorostowska-Wynimko J., Kus J., Skopinska-Rozewska E.
Journal of Physiology and Pharmacology. Supplement
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2007
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tom 58
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nr 5
20
Content available remote

Anti-asthmatic effects of volatile organic compounds from Chamaecyparis obtusa, Pinus densiflora, Pinus koraiensis, and Larix kaempferi wood panels

67%
Ahn C., Jang Y.-J., Kim J.-W., Park M.-J., Yoo Y.-M., Jeung E.-B.
Journal of Physiology and Pharmacology
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2018
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tom 69
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nr 6
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