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Potent antifungal properties of gallic acid in Sarcochlamys pulcherrima against Candida auris

100%
Akhtar N., Pandey D., Mannan A. U., Sarkar A., Sharma H., Kumar M., Ghosh A.
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
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2023
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tom 104
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nr 2
2

Time-dependent modification of model membrane properties by benzylammonium chlorides

100%
Gabrielska J., Sarapuk J., Kleszczynska H., Przestalski S.
Polish Journal of Environmental Studies
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1993
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tom 02
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nr 3
The nature of the interaction between some strong antifungal compounds and model membranes was studied. It was found that these compounds (N-dodecyl-N,N-dimethyl-N-/3- (β-methyl-β-nitrovinyl 1-6-methoxybenzyl/ammonium chloride and its derivatives) significantly change the properties of liposomes, planar lipid bilayers (BLM) and erythrocytes. The changes observed (i.e., release of praseodymium ions from liposomes and gradually diminished stability of BLM) in the presence of the compounds studied, as well as hemolysis of red blood cells, were time-dependent. It was also found that they depended on the polar head structure of the compounds.
3

Antifungal activity of thionated analogues of Nva-FMDP and Lys-Nva-FMDP

67%
Nowak-Jary J., Andruszkiewicz R.
Polish Journal of Microbiology
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2009
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tom 58
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nr 4
295-299
The antifungal activity of synthetic endothiopeptdides, i.e. NvaΨ [CSNH]-FMDP and LysΨ [CSNH]-NvaΨ [CSNH]-FMDP was studied in medium containing blood serum, against selected Candida strains; Candida albicans Gu4 (fluconazole sensitive), C. albicans Gu5 (fluconazole resistant), C. albicans ATCC 10231, Candida krusei DSM 6128 and Candidaparapsilosis DSM 5784. Although thiopeptide bonds in the tested peptides increased their stability in blood serum, their antifungal activity, however, drastically decreased in comparison with the peptides containing non-modified peptide bonds. Moreover, the inhibitory activity towards glucosamine-6-phosphate synthase of thionated synthetic analogue of FMDP was performed. The thiopeptdide bond also influenced its inhibitory properties against enzyme from C. albicans.
4
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From research on the use of chiral ionic liquids with a natural origin substituent for wood protection

67%
Zabielska-Matejuk J., Feder-Kubis J., Stangierska A.
Annals of Warsaw University of Life Sciences - SGGW. Forestry and Wood Technology
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2014
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tom 88
From research on the use of chiral ionic liquids with a natural origin substituenl for wood proteclion. Antifungal activities of chiral ionic liquids - menthoxymethylimidazolium derivates against brown-rot decay fungus (Coniophora puteana), white-rot decay fungus (Trametes versicolor) and blue-stain fungus (Sclerophoma pithyophila) were determined using screening agar-plate and agar-block methods. Results from antifungal tests revealed that 1-hexyl-3-[(1R,2S,5R)-(-)menthoxymethyl]imidazolium chloride exhibited the strongest antifungal activity against wood decay fungi (basidiomycetes) compared with the commercial didecyldimethylammonium chloride. Whereas compound with twelve carbons alkyl substituent has a weak antifungal activity. The infrared spectral analysis (FTIR ATR) confirmed that chiral imidazolium ionic liquids were built into the structure of the treated wood.
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