Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: antiangiogenic therapy

Sortuj według:

Ogranicz wyniki do:

Non-responsiveness and tachyphylaxis to anti-vascular endothelial growth factor treatment in naive patients with exudative age-related macular degeneration

100%

Zuber-Laskawiec K., Kubicka-Trzaska A., Karska-Basta I., Pociej-Marciniak W., Romanowska-Dixon B.

Journal of Physiology and Pharmacology

2019

tom 70

nr 5

Preparation and characterization of cytotoxic immunoliposomes for the simultaneous inhibition of angiogenesis and tumor growth

86%

Schwendener R. A.

Cellular and Molecular Biology Letters

1999

tom 04

nr 2

Combination of IL-12 gene therapy and CTX chemotherapy inhibits growth of primary B16[F10] melanoma tumors in mice

72%

Mitrus I., Delic K., Wrobel N., Missol-Kolka E., Szala S.

Acta Biochimica Polonica

2006

tom 53

nr 2

We investigated suppression of murine B16(F10) melanoma tumor growth following a therapy which involved concomitant administration of cyclophosphamide and plasmid DNA bearing interleukin-12 gene. Since both therapeutic factors display antiangiogenic capabilities, we assumed that their use in blocking the formation of new blood vessels would result in augmented inhibition of tumor growth. This combined therapy regimen indeed resulted in a considerable suppression of tumor growth. We observed a statistically significant extension of treated animals' lifespan. Interestingly, the therapeutic effect was also obtained using a plasmid without an interleukin gene insert. This observation suggests that plasmid DNA, which has been widely applied for treating neoplastic tumors, contains element(s) that elicit immune response in mice.

Ograniczanie wyników

1 Acta Biochimica Polonica

1 Cellular and Molecular Biology Letters

1 Journal of Physiology and Pharmacology

1 Delic K.

1 Karska-Basta I.

1 Kubicka-Trzaska A.

1 Missol-Kolka E.

1 Mitrus I.

1 Pociej-Marciniak W.

1 Romanowska-Dixon B.

1 Schwendener R. A.

1 Szala S.

1 Wrobel N.

1 Zuber-Laskawiec K.

1 2019

1 2006

1 1999

Wyniki wyszukiwania

Non-responsiveness and tachyphylaxis to anti-vascular endothelial growth factor treatment in naive patients with exudative age-related macular degeneration

Preparation and characterization of cytotoxic immunoliposomes for the simultaneous inhibition of angiogenesis and tumor growth

Combination of IL-12 gene therapy and CTX chemotherapy inhibits growth of primary B16[F10] melanoma tumors in mice