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Background: Dietary supplements (DSs) are concentrated sources of nutrients and/or other substances, whose purpose is to supplement the normal diet. Their consumption in Poland has been on the rise, leading to numerous concerns. However, current legislation does not provide any background for a relevant pharmacovigilance system. Therefore, little is known about their adverse effects (AEs) or patterns of use in Poland. To shed some light on this, we conducted a nationwide survey. Aim of the study: To assess the prevalence of, and the reasons for, the use of dietary supplements in Poland via national survey with a collection and an analyse of supposed adverse effects of dietary supplements. Material and methods: The study was conducted using an online survey based on the original questionnaire. In this report, we present the results of the analysis of the first 200 responses. Results: As many as 55.5% (111) of respondents were ‘definitely sure’ or ‘rather sure’ about DSs safety. However, 70.5% (141) believed that they could have negative effects. Over 3/4 (153) of respondents used DSs themselves, and 61.0% (122) used them within last 12 months. Of those using DSs, 11.1% (17) reported diverse Aes, with GI tract irritation and mental disturbances being the most common (experienced by 35.3% (6), and 17.6% (3) of those reporting AE s, respectively). Conclusions: Respondents had mixed feelings about DS safety. Despite that, they used these products frequently. Of a note is high incidence of adverse effects experienced by DS users. This undoubtedly points to the need for a relevant pharmacovigilance system.
In arid and semiarid regions, soil salinity causes the salt stress in plants and negatively affects the crop production. In this respect, organic farming practices are becoming the foreground as applications that are sensitive to the environment and support sustainability in agriculture. This study aimed to explain the role of vermicompost (VC) for reducing the effect of salt stress on lettuce (Lactuca sativa var. crispa) plant. The experiments were performed with different concentrations of VC (0, 2.5 and 5% VC on a weight per weight basis of soil-w/w) and salt stress treatments (4 and 8 dS m–1 NaCl levels). Under salt stress, shoot height, relative water content (RWC), stomatal conductance (gs), chlorophyll a (Chla) content decreased, while electrolyte leakage (EL), malondialdehyde (MDA) contents and superoxide dismutase (SOD) and catalase (CAT) activities significantly increased in parallel with the severity of the stress. In this study, VC under the salinity stress significantly increased the RWC, gs and Chla, Chlt and carotenoid contents in the leaf tissues; however, MDA and EL contents decreased and SOD and CAT activities increased compared to the controls. In all levels of NaCl, the 5% ratio of VC significantly reduced the negative effects of salinity.
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