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In the present study, we aimed to investigate for the first time the seroprevalence of feline coronaviruses (FCoV) in Van cats kept in a multiple-cat environment. A total of 24 male and 46 female Van cats aged between two months and nine years were used in the study. FCoV antibodies were determined using the commercial feline coronavirus antibody ELISA kit. The cats were examined clinically before blood sampling. No clinical signs of feline infectious peritonitis diseases were observed in the cats. But, out of the 70 cats, 38 (54.3%) showed seropositivity to FCoV. When the results were examined with regard to gender, 28 (60.9%) of female cats, and 10 (41.7%) of male cats were seropositive. When the results were examined with regard to age, out of the 18 cats aged between two months and one year, three (16%) were seropositive, out of the 10 cats aged between one to two years - eight (80%), out of the 27 cats aged between two to five years - 15 (55.5%), out of the 13 cats aged between five to eight years - 11 (84%), and all cats (two) aged over eight years showed seropositive reaction to FCoV.
This aim of the study was to determine the activity of ADA serum and isoenzyme in feline retroviral infections. The study involved 6 FeLV seropositive, 4 FIV seropositive and 10 healthy seronegative cats aged between 1-8 years. Haematological, serum enzyme acivity (AST; ALT; ALP; GGT) as well as ADA serum and isoenzyme activity were determined in all the cats. Haematological parameters were within the normal range except for the platelet count in FIV seropositive cats (p<0.05). Serum enzyme activity was unchanged except for the AST concentration in FeLV and FIV seropositive cats compared to the healthy subjects. ADA serum and ADA1 concentrations were lower in the seropositive group than in the seronegative group. However, the decrease in ADA serum and ADA1 concentrations in FIV seropositive cats (p<0.01) was more significant than that of FeLV seropositive cats (p<0.05). In conclusion, decreased ADA and ADA1 activity in feline retrovirus infections may be significant.
The pathomorphological and immunohistochemical features of cholangiocarcinoma in an 11-year-old female Van cat were described. At necropsy, the primary tumour was determined in the liver. The tumour was greyish-white, firm, and multinodular. The size of these nodules ranged between 1 cm and 3 cm. There were metastases in the mesentery, portal lymph nodes, peritoneum, and lung. Immunohistochemically, the tumour cells showed positive immunoreactivity for S100 and cytokeratin, and negative for α-fetoprotein. According to morphological and immunohistochemical findings, this tumour was defined as a cholangiocarcinoma.
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