Wyniki wyszukiwania

1

Msp18, the repetitive sequence specifically interacting with nuclear matrix of rat testis cells

100%

Rzeszowska-Wolny J., Rogolinski J.

Acta Biochimica Polonica

|

1994

|

tom 41

|

nr 4

The nuclear matrix bound DNA fraction of rat testis showed enrichment in repetitive sequences found in the 450 bp band after gel electrophoresis of the Mspl digested rat DNA. DNA fragments isolated from this band were cloned. DNA of the clone pMspI8 showed homology to some representatives of rat LINE sequence family, and complcxcd in vitro more efficiently with testes nuclear matrix proteins than with yeast ARS1 sequence containing the matrix association region (MAR) or DNA from an other clone, MspI19. Western blot analysis showed that MspI8 sequence interacts with testes matrix protein of about 120 kDa.

2

Some aspects of the copper(II) - DNA interaction

86%

Pawlowski T., Gulanowski B., Swiatek J., Gasiorowski K., Kozlowski H.

Acta Biochimica Polonica

|

1989

|

tom 36

|

nr 1

3

Interactions of rat repetitive sequence MspI8 with nuclear matrix proteins during spermatogenesis

86%

Rogolinski J., Widlak P., Rzeszowska-Wolny J.

Acta Biochimica Polonica

|

1996

|

tom 43

|

nr 2

Using the Southwestern blot analysis we have studied the interactions between rat repetitive sequence MspI8 and the nuclear matrix proteins of rat testis cells. Starting from 2 weeks the young to adult animals showed differences in type of testis nuclear matrix proteins recognizing the MspI8 sequence. The same sets of nuclear matrix proteins were detected in some fractions enriched in spermatocytes and spermatides and obtained after fractionation of testis cells of aduit animals by the velocity sedimentation technique.

4

New carbocyclic analogues of netropsin: synthesis and inhibition of topoisomerases

72%

Puckowska A., Bielawski K., Bielawska A., Rozanski A.

Acta Biochimica Polonica

|

2002

|

tom 49

|

nr 1

A series of carbocyclic analogues of netropsin were synthesized and evaluated for their capacity to inhibit human topoisomerases I and II in vitro. The compounds are oligopeptides containing 1,4-di- and 1,2,5-trisubstituted benzene rings and unsubstituted N-terminal NH2 groups. Compounds 4-7 consist of two netropsin-like units linked by aliphatic (tetra- and hexamethylene) chains. In the topoisomerase I and II assay, the relaxation of pBR322 plasmid was inhibited by compounds 4-7 at 100 uM concentration.

5

The effect of doxorubicin on rats that received toxic and carcinogenic benzo[a]pyrene

58%

Cosan D., Basaran A., Gunes H. V., Degirmenci I., Aral E.

Folia Histochemica et Cytobiologica

|

2008

|

tom 46

|

nr 3

367-372

6

Effect of ethanol on structural transitions of DNA and polyphosphates under Ca2plus ions action in mixed solutions

58%

Hackl E. V., Blagoi Y. P.

Acta Biochimica Polonica

|

2000

|

tom 47

|

nr 1

In the present work using the IR spectroscopy method the effect of ethanol on structural transitions of DNA and polyphosphates under the action of Ca2+ ions in mixed solutions containing ethanol (0-25 vol.%) was studied. It was shown that, on its interaction with Ca2+ ions, in aqueous and mixed solutions DNA becomes transformed into compact form. With the increase of concentration of ethanol the degree of Ca2+-induced DNA compactisation rises. It was found that, in mixed solutions containing ethanol, Ca2+-induced DNA compactisation depends not only on the solution's dielectric permeability but also on the solution structure. On stabilisation of the water structure in the presence of low ethanol concentrations a stabilisation of the DNA macromolecule occurs that leads to the increase of the Ca2+ ion concentration necessary for DNA compactisation. Comparison of the effects of ethanol on Ca2+-induced structural transitions in DNA and polyphosphates in mixed solvents permits to suppose that at alcohol concentrations in solution resulting in disruption of the water spatial structure, some peculiarities are observed in the behavior of those molecules whose hydrophobic interactions are essential.

Ograniczanie wyników

5 Acta Biochimica Polonica

1 Folia Histochemica et Cytobiologica

2 Rogolinski J.

2 Rzeszowska-Wolny J.

1 Aral E.

1 Basaran A.

1 Bielawska A.

1 Bielawski K.

1 Blagoi Y. P.

1 Cosan D.

1 Degirmenci I.

1 Gasiorowski K.

1 Gulanowski B.

1 Gunes H. V.

1 Hackl E. V.

1 Kozlowski H.

1 Pawlowski T.

1 Puckowska A.

1 Rozanski A.

1 Swiatek J.

1 Widlak P.

1 2008

1 2002

1 2000

1 1996

1 1994

1 1989

Msp18, the repetitive sequence specifically interacting with nuclear matrix of rat testis cells

Some aspects of the copper(II) - DNA interaction

Interactions of rat repetitive sequence MspI8 with nuclear matrix proteins during spermatogenesis

New carbocyclic analogues of netropsin: synthesis and inhibition of topoisomerases

The effect of doxorubicin on rats that received toxic and carcinogenic benzo[a]pyrene

Effect of ethanol on structural transitions of DNA and polyphosphates under Ca2plus ions action in mixed solutions