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1

Antimicrobial activity of natural dyes obtained from Terminalia arjuna (Roxb.) Wight and Arn barks

100%
Saivaraj S., Chandramohan G.
World Scientific News
|
2018
|
tom 98
2

Anti-cancer activity of Indoneesiella echioides (L.) Nees leaves using KB cells

100%
Elaiyaraja A., Chandramohan G.
World Scientific News
|
2018
|
tom 98
3

Isolation and characterization of 4’,7-dihydroxy isoflavone from Indoneesiella echioides (L.) Nees plant leaves

100%
Elaiyaraja A., Chandramohan G.
World Scientific News
|
2016
|
tom 55
4

Phytochemical screening, antioxidant and antimicrobial activities of Indoneesiella echioides (L.) Nees leaves

81%
Elaiyaraja A., Chandramohan G., Mariajancyrani J., Jayabharathi G.
World Scientific News
|
2015
|
tom 21
5
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Antimicrobial activity of Crinum defixum Ker - Gawler Leaves

81%
Elaiyaraja A., Chandramohan G., Mariajancyrani J.
International Letters of Natural Sciences
|
2015
|
tom 46
Crinum defixum Ker - Gawler is a bulbous herb which has widely used in indigenous medicine for many diseases; mainly leaf and bulb extracts are of medicinal importance. Leaf extract is used as a treatment for pimples, body-ache, dropsy, carbuncle, paronychia, leprosy, fever and diarrhoea. The bulbs are crushed and applied on to piles and itching. The present study to determine the possible phytochemicals and antimicrobial activity of various leaf extracts of Crinum defixum Ker - Gawler plant. The phytochemical screening demonstrated the presence different types compound like flavonoids, tannins, phenolic compounds, saponins and glycosides. The ethanol, methanol and crude extracts of Crinum defixum Ker - Gawler showed significant antibacterial activity against Escherichia coli, Staphylococcus aureus, pseudomonas aeruginosa, proteus vulgaris and antifungal activity against Candida albicans, Aspergillus flavus when compare to different concentrations (μg/mL). The antimicrobial potential of test compounds was determined on the basis of mean diameter of zone of inhibition around the disk in millimetres. Thus, the present findings revealed the medicinal potential of Crinum defixum Ker - Gawler to develop a drug against various human ailments.
6
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Effect of camel milk on the activities of ATPases in normal and streptozotocin-diabetic rats

71%
Al-Numair K. S., Chandramohan G., Kamalakkannan N., Alsaif M. A., Sundaraselvan G.
Polish Journal of Food and Nutrition Sciences
|
2010
|
tom 60
|
nr 4
Diabetes mellitus is the world’s largest endocrine disorder resulting in multiple aetiologies, involving metabolic disorders of carbohydrate, fat and protein. All forms of diabetes are due to a decrease in the circulating concentration of insulin (insulin deficiency) and a decrease in the response of peripheral tissues to insulin i.e., insulin resistance. According to the World Health Organization projections, the prevalence of diabetes is likely to increase by 35% by the year 2025. In this study, the streptozotocin (STZ)-induced diabetic rats, the activities of membrane-bound adenosine triphosphatases (ATPases) are altered in erythrocytes and in tissues such as liver and kidney. Albino Wistar rats were rendered diabetic by a single intraperitoneal injection of STZ (40 mg/kg body weight). Diabetic rats exhibited significantly (p<0.05) increased levels of plasma glucose and decreased levels of plasma insulin. The activities of total ATPases, (Na++K+)-ATPase, Ca2+-ATPase and Mg2+-ATPase were significantly (p<0.05) decreased in diabetic control rats. Control and diabetic rats were treated with camel milk (250 mL/day) for a period of 45 days. A group of diabetic rats were also treated with glibenclamide (600 μg/kg body weight). After the treatment period, a significant (p<0.05) decrease in the levels of glucose and increase in the levels of plasma insulin and the activities of ATPases in erythrocytes and tissues were observed in diabetic rats treated with camel milk. A similar effect is also observed in the glibenclamide treated rats. But, control rats treated with camel milk did not show any significant (p<0.05) effect in any of the parameters studied. Our study shows that camel milk has the potential to restore the deranged activities of membrane-bound ATPases in STZ-diabetic rats. Further detailed investigation is necessary to find out its mechanism of action.
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