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The possible role of coagulatory disorders in pathogenesis of Legg-Calve-Perthes disease (Lepo) and osteochondrosis (OC) was examined. A decrease in protein C level in dogs with LCPD (94.31±4.74%) in comparison with healthy dogs (95.8±6.35%) was observed. Moreover, in OC affected animals, the value varied between 92.25±2.5% and 94.33±5.5%. The mean plasma fibrinogen level in control group was 2.69±0.65 mg/mL, whereas in OC groups significantly higher values were found. Platelets number varied between individuals but was within normal range in all groups. Taking into account a decrease in protein C plasma level and an increase in fibrinogen concentration, the relationship between developmental diseases and coagulation disorders was revealed in dogs.
The paper presents preliminary results of the implantation of calcium sulfate type Hartform HF1 developed at the Institute of Glass and Ceramics in Warsaw. The study was conducted on 10 New Zealand White rabbits, in which after tibial osteotomy the biomateriał was implanted directly into the fracture site. The animals were divided into two groups based on the method of fracture stabilisation: intramedullary pinning using Kirschner wires in one group and acrylic external fixator in the other. After 12 weeks, bone union was observed in all animals as estimated by clinical and radiological findings. Histological tests revealed resorption of the biomateriał into the bone fracture area. It was concluded that type Hartform 1 calcium sulfate can be used as a biomateriał in veterinary orthopedics. Due to the lack of observable side effects during implantation and resorption, the material can be considered as a valuable ingredient in composite biomaterials containing calcium sulfate.
Ozone is a triatomic allotrope of oxygen that can be produced in specially designed machines: ozone generators (ozonators). It breaks down to dioxygen (O2) and active atomic oxygen (O), which is a very strong oxidant. Due to the fact that its bactericidal, virucidal and fungicidal activities are 50 times more powerful than those of chlorine, ozone could be used in a wide range of applications, including disinfection, disinfestation and deodorization. Biochemical properties of ozone make it useful in both human and animal medicine. Ozone therapy has been applied in the treatment of cardiovascular and gastrointestinal tract diseases, many viral, bacterial and fungal infections, corneal diseases, skin disorders, as well as in inflammatory and degenerative joint diseases. Various forms of ozone are utilized for medical purposes, for example, ozone/oxygene mixture, dressing covered with ozonated water or oil, ozonated infusion fluids and ozonated autohemotherapy (AHT). Medical ozone appeared to be successful in the treatment of antibiotic-resistant infections, infected and nonhealing wounds. When properly conducted, ozone therapy is safe and non-toxic, and should therefore be widely used in veterinary and human medicine practice.
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