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The aim of this research is to identify and analyse the situation of residents of selected nursing homes. The study covers residents of two nursing homes in the Podkarpackie region. Nottingham Health Profile measure was used to assess their quality of life. Nursing homes' residents rate their energy and physical efficiency as the lowest. Motor system diseases and impaired vision as well as co-occurring chronic diseases significantly affect the QoL. Out of all areas physical efficiency and emotional condition have the greatest impact on the QoL. Women and widowed persons report a clearly worse QoL. Persons who have lived in a nursing home for less than a year have the worst perception of their QoL.
 The aim of the study was to determine the level of functional independence in adult patients with previously undiagnosed or untreated phenylketonuria (PKU). The study was conducted among 400 intellectually impaired adult residents of Social Welfare Homes in South-Eastern Poland born prior to the introduction of neonatal PKU screening programs. PKU was screened by filter paper test using tandem mass spectrometry methods, and confirmed by gas chromatography-mass spectrometric analysis of PKU organic acids in urine. Degree of functional independence included the assessment of activities of daily living (Barthel Index) and measures of balance and gait (Tinetti scale). Eleven individuals with previously untreated PKU were identified whereby eight presented with moderate disability and three with mild disability. Six had a high risk of falls and five had a moderate risk of falls. This study indicates that there is considerable number of undiagnosed PKU patients within the Polish population who require assessment and management in order to reduce the impact of the neurological and neuropsychiatric problems associated with the condition. Appropriate therapy for those with undiagnosed PKU should, in particular, address the risk of falls.
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