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Antioxidant and anti - inflammatory activities of a commercial noni juice revealed by carrageenan - induced paw edema

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Yilmazer N., Coskun C., Gurel-Gurevin E., Yaylim I., Eraltan E. H., Ikitimur-Armutak E. I.

Polish Journal of Veterinary Sciences

2016

tom 19

nr 3

This study aimed to investigate antioxidant and anti-inflammatory activities of a commercial product of noni (Morinda citrifolia) juice. Carrageenan-induced rat paw edema was employed as inflammatory model. One control and three experimental groups were formed. Experimental groups were administered noni juice alone, noni juice+carrageenan, and carrageenan alone. Oxidant and antioxidant capacity were determined by d-ROMs test and BAP test, respectively. Plasma concentrations of endothelin-1 and leptin were measured by ELISA. Measurements were performed at zero time and 2nd hour of inflammation. Oxidant capacity decreased in noni-received groups at 2nd hour (p=0.019). Antioxidant capacity of the group which received noni alone was found to be higher at 2nd hour (p=0.036). Plasma concentrations of endothelin-1 and leptin were notably lower in noni-received groups (p=0.001 and p=0.021, respectively). The results show that the commercial noni juice investigated has pronounced antioxidant and anti-inflammatory activities.

Ograniczanie wyników

1 Polish Journal of Veterinary Sciences

1 Coskun C.

1 Eraltan E. H.

1 Gurel-Gurevin E.

1 Ikitimur-Armutak E. I.

1 Yaylim I.

1 Yilmazer N.

1 2016

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Antioxidant and anti - inflammatory activities of a commercial noni juice revealed by carrageenan - induced paw edema