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In order to prevent the MMA syndrome in pigs there were administered a fimbrial vaccine based on K88, P987 and F41 antigens and Suimastivac containing the antigens of E. coli, Klebsiella pneumoniae, Staphylococcus aureus and Streptococcus faecalis. Vaccinations were conducted twice on 4 and 2 weeks before parturition. The fimbrial vaccine in a dose of 5 ml per animal was applied in 369 sows and Suimastivac in a dose of 10 ml in 78 sows and in a dose of 5 ml in 80 sows. Following vaccination with Suimastivac in a dose of 10 ml there was observed a decrease of MMA occurrence from 20 to 12.8 per cent. In other experimental groups no significant differences regarding morbidity of sows were noted.
Many cases of pleuropneumonia were observed in pigs aged 3—4 months on an industrial farm. In order to determine an optimal procedure there was performed an experiment on three groups of pigs. Group one containing 654 young pigs aged 6 weeks was given amoxacillin for 7 days at a dose of 12 g per 100 l of water. A vaccine against pleuropneumonia was administered the second group of young pigs (660 animals). The third group (660 young pigs) was vaccinated between 8 and 11 weeks of life against pleuropneumonia and in the period between vaccinations amoxacillin was administered for 7 days at a rate of 25 g per 100 kg of feed. Each experimental group of animals was compared with a control group comprising a nearing number of animals. The best results were observed in the third group mortality of 2.6 per cent compared with 7.7 per cent of death in the control group; daily weight gains were at 7.7 per cent higher than those in controls.
A probiotic Acid-Pack-4-Way produced by Alltech Center was ad­ministrated in a industrial farm: 636 piglets aged 4 weeks received the drug at the rale of 400 g per 100 kg of fodder (Grower) for 14 days. After 6 weeks it was found that 11.6 per cent of the animals in the experimental group were retarded in growth while in a control group receiving tylosin and furan after weaning the percentage of such piglets was 31.9. However, the death rate was higher in this group, Le. 11.7 per cent compared with 9.2 per cent in the control one. The probiotic was administred to 1334 pigs aged 3 months for two weeks at a dose of 400 g per 100 kg of dry fodder. Losses in the experimental group were 3.1 per cent and in the control 17.0 per cent although they received ronidasole during the adaptation period. The percentage of pigs with retarded growth was 22.5 in the experi­mental group and 30.8 in the control group. The cost analysis showed that the use of the probiotic in the period of pigs’ translocation was profitable.
Активным веществом в Tiamowet (Т) является полусинтетический антибиотик тиамулин. Tiamowet в дозе 1,0—1,2 на свинью за день применялся 5 дней в лечении энзоотического бронхогенного воспаления легких у са 3600 свиней с массой тела 30—50 кг. Клинические симптомы болезни исчезали через 2 дня лечения. Так же эффективен был Т. в лечении дизентерии свиней. Метафилактика дизентерии при применении Т. не принесла хороших эффектов. Отрицательной стороной применения Т. является его раздражающее действие на соединительные оболочки глаза и слизистую оболочку носа обслуживающего персонала.
Sows during or just after parturition were injected the following preparates contracting uterus: group I — 217 sows, oxvtocin 0,06 mg; group II — 156 sows, hypophysin 50 J.V.; group III — 111 animals, hypophysin 20 j.V. Control group consistetd of 487 sows. In all experimental groups interpartu­rient period was shortened by about 1—9 days camparing to controls. In group I percent of diarrhoeic piglets diminis­hed by 33,3, losses lowered by 2,1%, incidence of diseases in sows lowered by 3,7%, and the number of sows active in a successive reproductive cycle increased by 2,4% com­paring to controls. In groups I and II a mean number of progeny in a successive brood was significantly lower than that in control group. In group II percentage of sick sows lowered by 18,6% but number of moribund piglets and number of sows active in reproduction was comparable with controls. In group III a healthy state of sows and rearing of piglets were lower than in controls.
У 375 сивножаток применено по 2 мл Suisterol. Доза содержала 0,512 мг хoрионного гонадоrропина и 2 мг бензоата эстрадиола. Охоту показало 215 свиноматок (57,3%), из которых опоросились 132 (61,4%. Во II репродукционном цикле участвовало 46,2%, а в III — 22,8% самок. Контрольную группу составляло 140 свиноматок, покрытых в результате спонтанной охоты, из котрых опоросилось 78,6%. Во II репродукционном цикле участвовало 78.6%, а в III — 46,4% самок. В течение 3 репродукционных циклов в экспериментальной группе родилось 1899 поросят, т.е. на одну покрытую свиноматку приходилось 8,83 поросенка. В контрольной группе в 3 репродукционный циклах родилось 2078 поросят, т.е. на одну покрытую сивноматку проиходилось 14,84 поросенка. Разницы в плодовитости между группами оказались статистически существенными. Самки, как свиноматки подвергнутые гормональной стимуляции, показывали пониженную репродукицонную способность по сравнению с самками, покрытыми как свиноматки в результате спонтанной охоты.
Sows (676) at the age of 1—5 years weighing 100—200 kg divided into 7 groups were given at about 108 day of pregnancy parenterally a neutral sodium selenite at doses from 0.04 to 0.28 mg of Se/kg b.w. For the studies 7 control groups of sows of a similar tern of partirition were incuded. A significat decrease of the MMA frequency was noted in group IV (0.11—0.23 mg of Se/kg b.w.) in which the MMA syndrom was diagnosed in 30.0% of ani­mals in comparison to a control group. Similar effects were noted in group VII (0.14—0.28 mg of Se/kg b.w.) in which the MMA syndrom was diagnosed in 56.2% of animals in comparison to a control group.
Six consecutive enzooties of SVD in the years of 1973/1978 were described. The first enzooty involved almost the total number of pigs on a farm (approximately 3500 animals). In 8.4 per cent the disease many abortions at different stages of pregnancy were noted. Out of 296 pigs with nervous symptoms of the disease, 122 animals were treated by sedative drugs and cardiatic ones. In the cured group of animals, 53.3 per cent recovered compared with only one pig with the symptoms of cahexia out of 174 control animals. In the recovered animals the titres of seroneutralizing antibodies ranged from 80 to 160 through out the year. The same titres of antibodies were noted in piglets coming from convalescent sows. The convalescent pigs were resistant to natural and artificial infections with SVDV. The consecutive enzooties with SVDV were of mild course without nervous symptoms of the disease and concerned 0.3-1.0 per cent of pigs; no animal died.
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