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Twenty five women (21 to 50 years old) with genetic diseases (phenylketonuria, Down’s syndrome, achondroplasia, epilepsy), patients of the II Maxillo-Facial Surgery Clinic of the Medical University of Warsaw, were examined for the pre-treatment status of the oral cavity and the occurrence of oral protozoans, Entamoeba gingivalis and/or Trichomonas tenax. On the basis of the clinical characteristics and light and transmission electron microscopic examination, relationship between periodontal condition and presence of the oral protozoans were analysed and factors which may play the main role in the maintenance of the infection in these patients were determined. The highest prevalence of infection with E. gingivalis and T. tenax was noted in the 41-50 year age group in which more than 88% of the patients were infected. In 11 among of 20 of the cases with periodontal disease, infection with T. tenax, and/or E. gingivalis occurred. In 10 among of 16 of the individuals with limited mobility the oral protozoans was present. Our studies indicate that age as well as limited mobility of the patients examined resulting in difficulties with maintaining of good hygiene of oral cavity may play an important role in occurrence of infection with the oral protozoans and inflammatory processes in gingiva and periodontium.
The aim of this work was to study clinical changes and microorganisms in mouths of three patient groups: with congenital disorders (Cd), dialyzed (D) and control (C). Fifty five patients, 20 to 62 years old were assessed. Swabs and samples of periodontal tissue were used for microscopical study to detect of protozoans and for bacterial and fungal cultures. E. Gingivalis and T. tenax were found in all groups. Three out of Cd patients were infected with Acanthamoeba sp. Fecal bacteria were more often found in D than Cd. In all 30-40 years old D patients, fecal bacteria and various strains of C. albicans occurred. We found that systemie diseases favour instabilities in mouths changing interrelations between protozoa, bacteria and fungi. It may increase risk of clinical complications.
The aim of this study was to compare the oral cavity status with the species composition of microorganisms colonizing the mouth of patients with or without systemic diseases. Seventy-seven men and women, 19 to 65-years-old, of four groups: hemodialyzed patients (HD), kidney allograft recipients (Tx), congenitally disordered (Cd) and control (C) patients (without systemic diseases) were examined clinically for the oral cavity status and the microorganisms occurring in the mouth were identified. Swabs and samples taken from dental plaques, pockets and periodontium were used for light and electron microscopical studies as well as for protozoan, bacterial and fungal cultures. Entamoeba gingivalis and Trichomonas tenax were found in the HD, Tx, Cd and C groups (top prevalence 14, 14, 87.5 and 25%, respectively); free-living amoebae (with some features of Acanthamoeba sp.) also occurred in several cases. Staphylococcus aureus bacteria were found in 66% of Cd patients infected with the protozoans. Numerous fecal bacteria and/or fungi Candida albicans have been observed in 41-51-year-old Cd and HD patients. In all patient groups, it was the 41-51-year-olds who showed the highest prevalence of protozoans, bacteria and fungi. The results indicate that metabolic disabilities favour pathological changes in periodontal tissues and may influence the species composition of mixed protozoan, bacterial and/or fungal infections in various ways, in patients with different systemic diseases.
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